Tematy, które znajdują się w centrum naszych zainteresowań badawczych to między innymi :
Kierownik projektu: Róża Pawłowska
Typ projektu: Grant NCN, SONATA-13
Numer grantu: 2017/26/D/ST5/01046
Kierownik projektu: Arkadiusz Chworoś
Typ projektu: Grant NCN, OPUS-10
Numer grantu: 2015/19/B/ST5/03087
Kierownik projektu: Arkadiusz Chworoś
Typ projektu: Grant NCN, OPUS-3
Numer grantu: 2012/05/B/ST5/00364
Kierownik projektu: Arkadiusz Chworoś
Typ projektu: Grant NCN, OPUS-1
Numer grantu: 2011/01/B/NZ3/02090
Kierownik projektu: Arkadiusz Chworoś
Typ projektu: Grant MNiSW
Numer grantu: N302/643740
Aplikacje powstałe podczas pracy przy dokowaniach oraz modelowaniach molekularnych:
Modified nucleotides for chemical and enzymatic synthesis of therapeutic RNA
Anna Graczyk, Ewa Radzikowska-Cieciura, Renata Kaczmarek, Roza Pawlowska, Arkadiusz Chworos
Current Medicinal Chemistry, 2023, 30(11), 1320 – 1347
https://doi.org/10.2174/0929867330666221014111403
The ATP-dependent Pathways and Human Diseases
Justyna Suwara, Ewa Radzikowska-Cieciura, Arkadiusz Chworos, Roza Pawlowska
Current Medicinal Chemistry, 2023, 30(11), 1232 – 1255
https://doi.org/10.2174/0929867329666220322104552
Evaluation of the anti-diabetic activity of sea buckthorn pulp oils prepared with different extraction methods in human islet EndoC-betaH1 cells
Eliza Korkus, Grzegorz Dąbrowski, Marcin Szustak, Sylwester Czaplicki, Rafał Madaj, Arkadiusz Chworos, Maria Koziołkiewicz, Iwona Konopka, Edyta Gendaszewska-Darmach
Nutrition and Food Science, 2022, 27, 54–66
https://doi.org/10.1016/j.nfs.2022.05.002
Synthesis and Biological Studies of Novel Aminophosphonates and Their Metal Carbonyl Complexes (Fe, Ru)
Aneta Kosińska, David Virieux, Jean-Luc Pirat, Kamila Czarnecka, Małgorzata Girek, Paweł Szymański, Sławomir Wojtulewski, Saranya Vasudevan, Arkadiusz Chworos and Bogna Rudolf
Int. J. Mol. Sci., 2022, 23(15), 8091
https://doi.org/10.3390/ijms23158091
The epithelial-mesenchymal transition of A431 cells after treatment with ATP, ADP, AMP and adenosine
Roza Pawlowska, Julia Fastyn, Anna Graczyk, Ewa Radzikowska-Cieciura, Arkadiusz Chworos
FEBS Open BIO, 2022, 12, P-01.1-116, 109-109
In silico exploration of binding of selected bisphosphonate derivatives to placental alkaline phosphatase via docking and molecular dynamics
Rafal Madaj, Roza Pawlowska, Arkadiusz Chworos
Journal of Molecular Graphics and Modelling, 2021, 103, 107801,
https://doi.org/10.1016/j.jmgm.2020.107801
Target2DeNovoDrug: a novel programmatic tool for in silico-deep learning based de novo drug design for any target of interest
Rafal Madaj, Ben Geoffrey, Akhil Sanker, Pavan Preetham Valluri
Journal of Biomolecular Structure and Dynamics, 2021, 1-6,
https://doi.org/10.1080/07391102.2021.1898474
Batch Mode Reactor for 3,5-Dinitrosalicylic Acid Degradation by Phanerochaete chrysosporium
Rafał Madaj, Witold Sroczynski, Michal Sojka, Tomasz P. Olejnik and Elzbieta Sobiecka
Processes, 2021, 9(1), 105, 2-9,
https://doi.org/10.3390/pr9010105
Composites of Nucleic Acids and Boron Clusters (C2B10H12) as Functional Nanoparticles for Downregulation of EGFR Oncogene in Cancer Cells
Damian Kaniowski, Katarzyna Ebenryter-Olbińska, Katarzyna Kulik, Justyna Suwara, Wojciech Cypryk, Agata Jakóbik-Kolon, Zbigniew Leśnikowski and Barbara Nawrot
Int. J. Mol. Sci., 2021, 22(9), 4863,
https://doi.org/10.3390/ijms22094863
Gold nanoparticles as carriers for functional RNA nanostructures
Anna Graczyk, Roza Pawlowska, Arkadiusz Chworos
Bioconjugate Chemistry, 2021, 32(8), 1667-1674
https://doi.org/10.1021/acs.bioconjchem.1c00211
Tissue-Nonspecific Alkaline Phosphatase (TNAP) as enzyme involved in degradation of nucleotide analogues in the ligand docking and molecular dynamics approach.
Rafal Madaj, Bartlomiej Gostynski, Roza Pawlowska, Arkadiusz Chworos,
Biomolecules, 2021, 11(8), 1104, 1-16
https://doi.org/10.3390/biom11081104
Rossmann-toolbox: a deep learning-based protocol for the prediction and design of cofactor specificity in Rossmann fold proteins
Kamil Kamiński, Jan Ludwiczak, Maciej Jasiński, Adriana Bukala, Rafal Madaj, Krzysztof Szczepaniak, Stanisław Dunin-Horkawicz
Briefings in Bioinformatics, 2021, bbab371
https://doi.org/10.1093/bib/bbab371
Functional RNA-AuNP conjugates for gene expression regulation based on the GFP example
Anna Graczyk, Roza Pawlowska and Arkadiusz Chworos,
FEBS Open BIO, 2021, 11, P-01.2-21, 127-127
The adenosine carbocyclic analogue and its impact on human squamous carcinoma cells
Roza Pawlowska, Justyna Suwara, Beata Lukasik, Remigiusz Zurawinski, Arkadiusz Chworos
FEBS Open BIO, 2021, 11, P-08.2-40, 426-42
Anna Graczyk, Roza Pawlowska, Dominika Jedrzejczyk and Arkadiusz Chworos
Gold Nanoparticles in Conjunction with Nucleic Acids as a Modern Molecular System for Cellular Delivery
Molecules, 2020, 25, 204, 1-27
https://doi.org/10.3390/molecules25010204
Justyna Suwara, Beata Lukasik, Remigiusz Zurawinski, Roza Pawlowska and Arkadiusz Chworos
Highly Fluorescent Distyrylnaphthalene Derivatives as a Tool for Visualization of Cellular Membranes
Materials, 2020, 13(4), 951, 1-20
https://doi.org/10.3390/ma13040951
Rungsima Chollakup, Pimporn Uttayarat, Arkadiusz Chworos, Wirasak Smitthipong
Noncovalent sericin/chitosan scaffold: physical properties and low cytotoxicity effect
Int. J. Mol. Sci. 2020, 21(3), 775
https://doi.org/10.3390/ijms21030775
Pitchaya Pakornpadungsit, Thridsawan Prasopdee, Napachanok Mongkoldhumrongkul Swainson, Arkadiusz Chworos, Wirasak Smitthipong
DNA:chitosan complex, known as a drug delivery system, can create a porous scaffold
Polymer Testing, 2020, 83, 106333
https://doi.org/10.1016/j.polymertesting.2020.106333
Aneta Wróblewska, Justyna Śniechowska, Sławomir Kaźmierski, Ewelina Wielgus, Grzegorz D. Bujacz, Grzegorz Mlostoń, Arkadiusz Chworos, Justyna Suwara and Marek J. Potrzebowski
Application of 1-Hydroxy-4,5-Dimethyl-Imidazole 3-Oxide as Coformer in Formation of Pharmaceutical Cocrystals
Pharmaceutics 2020, 12, 359
https://doi.org/10.3390/pharmaceutics12040359
Beata Łukasik, Maciej Mikina, Marian Mikołajczyk, Roza Pawlowska and Remigiusz Zurawinski.
A novel route to a chiral building block for the preparation of cyclopentenyl carbocyclic nucleosides. Synthesis and anticancer activity of enantiomeric neplanocins A.
RSC Adv., 2020, 10, 31838–31847
https://doi.org/10.1039/d0ra06394k
Ben Geoffrey, Akhil Sanker, Rafal Madaj, Mario Sergio Valdés Tresanco, Manish Upadhyay, Judith Gracia. A program to automate the discovery of drugs for West Nile and Dengue virus— programmatic screening of over a billion compounds on PubChem, generation of drug leads and automated in silico modelling. Journal of Biomolecular Structure and Dynamics, 2020
https://doi.org/0.1080/07391102.2020.1856185
RNA Trimeric Nanoparticle for Gene Expression Regulating in a Model GFP System.
Dominika J. Jedrzejczyk and Arkadiusz Chworos.
ACS Synthetic Biology 2019, 8(3), 491-497
https://doi.org/10.1021/acssynbio.8b00319
Theoretical and experimental study on the effects of pH and surfactant on the internal charge transfer process in distyrylnaphthalene-based conjugated oligoelectrolytes.
Agnieszka Kowalska-Baron, Remigiusz Zurawinski, Beata Lukasik, Arkadiusz Chworos, Malgorzata Przybyt.
Spectrochimica Acta Part A, 2019, 216, 221–229
https://doi.org/10.1016/j.saa.2019.03.037
Multicomponent Conjugates of Anticancer Drugs and Monoclonal Antibody with PAMAM Dendrimers to Increase Efficacy of HER-2 Positive Breast Cancer Therapy
Monika Marcinkowska, Maciej Stanczyk, Anna Janaszewska, Ewelina Sobierajska, Arkadiusz Chworos, Barbara Klajnert-Maculewicz
Pharmaceutical Research, 2019, 36(11), 154
https://doi.org/10.1007/s11095-019-2683-7
Karolina Janik, Cezary Treda, Aneta Wlodarczyk, Joanna Peciak, Kamila Rosiak, Jolanta Zieba, Dagmara Grot, Adrianna Rutkowska, Roza Pawlowska, Waldemar Och, Piotr Rieske, Ewelina Stoczynska-Fidelus
A way to understand idiopathic senescence and apoptosis in primary glioblastoma cells – possible approaches to circumvent these phenomena.
BMC Cancer, 2019 19(1):923
https://doi: 10.1186/s12885-019-6130-2
Self-Assembling RNA Nanoparticle for Gene Expression Regulation in a Model System
Dominika Jedrzejczyk, Arkadiusz Chworos
ACS Synthetic Biol. 2019, 8(3):491-497
https://doi.org/10.1021/acssynbio.8b00319
Theoretical and experimental study on the electronic structure of distyrylnaphthalene-based conjugated oligoelectrolytes
Agnieszka Kowalska-Baron, Remigiusz Zurawinski, Beata Lukasik, Arkadiusz Chworos, Stanislaw Wysocki
J Luminescence 2018, 196:81-89
Conjugate of PAMAM Dendrimer, Doxorubicin and Monoclonal Antibody-Trastuzumab: The New Approach of a Well-Known Strategy
Monika Marcinkowska, Ewelina Sobierajska, Maciej Stanczyk, Anna Janaszewska, Arkadiusz Chworos, Barbara Klajnert-Maculewicz
Polymers 2018, 10(2):187
Self-assembly nucleic acid-based biopolymers: learn from the nature
Pitchaya Pakornpadungsit, Wirasak Smitthipong, Arkadiusz Chworos
J Pol Res 2018, 25(2):45
Solvent effects on the photophysical properties of distyrylnaphthalene-based conjugated oligoelectrolytes
Agnieszka Kowalska-Baron, Remigiusz Zurawinski, Beata Lukasik, Arkadiusz Chworos, Stanislaw Wysocki
J Luminescence 2017, 192:359-370
Composing RNA Nanostructures from a Syntax of RNA Structural Modules
Cody Geary, Arkadiusz Chworos, Erik Verzemnieks, Neil R. Voss, Luc Jaeger
Nano Lett. 2017, 17(11):7095-7101
Facile synthesis of fluorescent distyrylnaphthalene derivatives for bioapplications,
Beata Lukasik, Justyna Milczarek, Pawlowska Roza, Remigiusz Zurawinski, Arkadiusz Chworos
New J Chemistry 2017, 41 (15): 6977-6980
Fluorescence and confocal imaging of mammalian cells using conjugated oligoelectrolytes with phenylenevinylene core.
Justyna Milczarek, Roza Pawlowska, Remigiusz Zurawinski, Beata Lukasik, Logan E. Garner, Arkadiusz Chworos
J Photochem Photobiol B. 2017, 170:40-48
Designing synthetic RNA for delivery by nanoparticles
Dominika Jedrzejczyk, Edyta Gedaszewska-Darmach, Roza Pawlowska, Arkadiusz Chworos
J Phys Condens Matter. 2017 Mar 29;29(12):123001
Supported Fluid Lipid Bilayer as a Scaffold to Direct Assembly of RNA Nanostructures
Aleksandra P. Dabkowska, Agnes Michanek, Luc Jaeger, Arkadiusz Chworos, Tommy Nylander, Emma Sparr
RNA structures: methods and protocol, Methods in Molecular Biology, 2017, 1632:107-122
RNA model evaluation based on MD simulation of four tRNA analogs
Anna Grzybkowska, Dominika Jedrzejczyk, Rostkowski Michal, Arkadiusz Chworos, Agnieszka Dybala-Defratyka
RSC Adv. 2016, 104(6):101778-101789
RNA fragments mimicking tRNA analogs interact with cytochrome c
Roza Pawlowska, Magdalena Janicka, Dominika Jedrzejczyk, Arkadiusz Chworos
Mol. Biol. Rep., 2016, 43(4):295-304. doi: 10.1007/s11033-016-3954-6
The alpha-thio and/or beta-gamma-hypophosphate analogs of ATP as cofactors of T4 DNA ligase
Roza Pawlowska, Korczynski Dariusz, Barbara Nawrot, Wojciech J. Stec, Arkadiusz Chworos
Bioorg Chem. 2016:110-5. doi: 10.1016/j.bioorg.2016.06.003
Assembly of RNA nanostructures on supported lipid bilayers
Aleksandra P. Dabkowska, Agnes Michanek, Luc Jaeger, Michael Rabe, Arkadiusz Chworos, Fredrik Hook, Tommy Nylande, Emma Sparr
Nanoscale, 2015, 7(2), 583-596
Bio-inspired nucleic acids based materials
Arkadiusz Chworos and Wirasak Smitthipong
Bio-Based Composites for High-Performance Materials: From Strategy to Industrial Application
CRC Press, Taylor & Francis, 2015, chapter 2, 43-58
Phenylenevinylene conjugated oligoelectrolytes as fluorescent dyes for mammalian cell imaging
Paulina Gwozdzinska, Roza Pawlowska, Justyna Milczarek, Logan E. Garner, Alexander W. Thomas, Guillermo C. Bazan, Arkadiusz Chworos
Chemical Communications, 2014, 50 (94), 14859-14861
DNA-functionalized polystyrene particles and their controlled self-assembly
Rungsima Chollakup, Wirasak Smitthipong, Arkadiusz Chworos
RSC Advances, 2014, 4 (58), 30648-30653
Cytochrome c interaction with tRNA, the new properties of the known molecules
Roza Pawlowska, Dominika Jedrzejczyk, Magdalena Janicka, Anna Graczyk and Arkadiusz Chworos
Acta Biochimica Polonica, 2014, S1, P7.35, 155
Structural analogs of tRNA form a Complex with Cytochrome C
Roza Pawlowska, Dominika Jedrzejczyk, Magdalena Janicka, Arkadiusz Chworos
FEBS Letters 281, 2014, S1, 398
Anna Graczyk, Dominika Jedrzejczyk, Roza Pawlowska, Arkadiusz Chworos
The Complex of tRNA with Cytochrome C in Gel Studies
Collection Symposium Series, 2014, 14, 283-284
Rational design of RNA nanoparticles and nanoarrays
Arkadiusz Chworos
RNA Nanotechnology, Pan Stanford Publishing, 2014, chapter 11, 213-234
RNA nanoparticles for gene expression regulation
Roza Pawlowska, Paulina Gwozdzinska and Arkadiusz Chworos
Nucleic Acids Nanotechnologies in Medicine: Diagnosis and Treatment of Diseases
Springer, 2013, chapter 11, 263-290
Supramolecular cooperative-assembly of polyelectrolyte films
Rungsima Chollakup, Wirasak Smitthipong and Arkadiusz Chworos
RSC Advances, 2013, 3, 4745-4749
Distyrylbenzene oligoelectrolyte (DSBN+) for human cervical carcinoma cells imaging
Roza Pawlowska, Paulina Gwozdzinska, Logan Garner and Arkadiusz Chworos
MRS Symposium Proceedings, Cambridge University Press, 2013, vol. 1569
From Bioorganic Chemistry to Chemical Biology (Od chemii bioorganicznej do biologii chemicznej)
Wojciech T. Markiewicz, Henryk Koroniak, Arkadiusz Chworos, Piotr Mucha, Jan Barciszewski
Misja Nauk Chemicznych, Wydawnictwo Nauka I Innowacja, 2011, 27, 109-124 (book chapter)
Effect of the Peptide Secondary Structure on the Peptide Amphiphile Supramolecular Structure and Interactions
Dimitris Missirlis, Arkadiusz Chworos, Caroline J. Fu, Htet A. Khant, Daniel V. Krogstad, Matthew Tirrell
Langmuir, 2011, 27, 6163_6170
Self-Assembly of an Optically Active Conjugated Oligoelectrolyte
Julia H. Ortony, Tirtha Chatterjee, Logan E. Garner, Arkadiusz Chworos, Alexander Mikhailovsky, Edward J. Kramer Guillermo C. Bazan
JACS, 2011, 133, 8380-8387
Promoting RNA helical stacking via A-minor junctions
Cody Geary, Arkadiusz Chworos, Luc Jaeger
Nucleic Acids Research, 2011, 39(2), 1066-1080
Self-Assembling RNA Nanorings Based on RNAI/II Inverse Kissing Complexes
Wade W. Grabow, Paul Zakrevsky, Kirill Afonin, Arkadiusz Chworos, Bruce A. Shapiro, Luc Jaeger
Nano Lett., 2011, 11(2), 878-887
Improved isolation of proteins tagged with glutathione S-transferase
Nicholas K. Vinckier, Arkadiusz Chworos, Stanley M. Parsons
Protein Expression And Purification, 2011, 75(2), 161-164
A polyhedron made of tRNAs
Isil Severcan, Cody Geary, Arkadiusz Chworos, Neil Voss, Erica Jacovetty, Luc Jaeger
Nature Chemistry, 2010, 2, 772-779 (high impact)
Modification of the Optoelectronic Properties of Membranes via Insertion of Amphiphilic Phenylenevinylene Oligoelectrolytes
Logan E. Garner, Juhyun Park, Scott M. Dyar, Arkadiusz Chworos, James J. Sumner, Guillermo C. Bazan
JACS, 2010, 132 (29), 10042-10052
Identification of Bacteria by Conjugated Oligoelectrolyte/Single-Stranded DNA Electrostatic Complexes
Aidee Duarte, Arkadiusz Chworos, Suvi F. Flagan, Grady Hanrahan, Guillermo C. Bazan
JACS, 2010, 132 (36), 12562-12564
Specific interaction of DNA-functionalized polymer colloids
Rungsima Chollakup, Wirasak Smitthipong and Arkadiusz Chworos
Polymer Chemistry, 2010, 1 (5), 658-662
A Tripod Molecular Tip for Single Molecule Ligand-Receptor Force Spectroscopy by AFM
Michael E. Drew, Arkadiusz Chworos, Emin Oroudjev, Helen Hansma, Yoko Yamakoshi
Langmuir, 2010, 26 (10), 7117-7125
Automatic Analysis of Conjugated Polyelectrolytes – DNA Interactions Based on Sequential Analysis of AFM Imaging
Arkadiusz Chworos, Boguslaw Obara
IEEE Transactions on Nanotechnology, 8, 2009, 457-462
Noncovalent Supramolecular Self-assembling Polyelectrolyte: Nucleic Acid Based Materials
Wirasak Smitthipong, Thorsten Neumann, Surekha Gajria, Youli Li, Arkadiusz Chworos, Luc Jaeger, and Matthew Tirrell
Macromolecules, 2009, 10, 221-228
Square-Shaped RNA Particles from Different RNA Folds
Isil Severcan, Cody Geary, Erik Verzemnieks, Arkadiusz Chworos, and Luc Jaeger
Nano Letters, 2009, vol 9, issue 3, 1270-1277
Preliminary structural investigations of the Eut-L shell protein of the ethanolamine ammonia-lyase metabolosome of Escherichia coli
Kiel Nikolakakis, Akashi Ohtaki, Keith Newton, Arkadiusz Chworos and Martin Sagermann
Acta Crystallographica, 2009, F65, 128-132
Anatomy and Growth Characteristics of Conjugated Polyelectrolyte/DNA Aggregates.
Chunyan Chi, Arkadiusz Chworos, Jinping Zhang, Alexander Mikhailovsky and Guillermo C. Bazan
Advanced Functional Materials, 18, 2008, 3606-3612 (journal cover)
Self-assembled Materials Containing Complementary Nucleobase Molecular Recognition.
Wirasak Smitthipong, Arkadiusz Chworos, Brian Lin, Thorsten Neumann, Surekha Gajria, Luc Jaeger and Matthew Tirrell
Mater. Res. Soc. Symp. Proc., 2008, 1094
Supramolecular Materials Comprising Nucleic Acid Biopolymers.
Wirasak Smitthipong, Thorsten Neumann, Arkadiusz Chworos, Luc Jaeger and Matthew Tirrell
Macromol. Symp., 264, 2008, 13-17
Nucleic acid foldamers: design, engineering and selection of programmable bio-materials with recognition, catalytic and self-assembly properties.
Arkadiusz Chworos and Luc Jaeger
Foldamer, by Wiley, 2007, Chapter 10 (book chapter)
Sculpting Responsive, Informational Nano-Particles with RNA
Cody Geary, Isil Severcan, Erik Verzemnieks, Arkadiusz Chworos and Luc Jaeger
Journal of Biomolecular Structure & Dynamics, 2007, 24, 703-704
The design and characterization of modular polyhedral architectures made of RNA
Isil Severcan, Cody Geary, Arkadiusz Chworos, Luc Jaeger
Biophysical Journal, 2007, 350a-351a Suppl. S
The architectonics of programmable RNA and DNA nanostructures
Luc Jaeger and Arkadiusz Chworos
Current Opinion of Structural Biology, 2006, 4, 531-543 (review)
From RNA Tectonics to Programmable Jigsaw Puzzles Made of RNA
Arkadiusz Chworos and Luc Jaeger
Proceedings Foundations of Nanoscience, 2005, 157-162
Controlled Spacing of Cationic Gold Nanoparticles by Nanocrown RNA
Alexey Y. Koyfman, Gary Braun, Sergei Magonov, Arkadiusz Chworos, Norbert O. Reich, and Luc Jaeger
JACS, 2005, 127, 11886-11887
Thermal stability analysis of self-assembling tRNA tecto-squares
Isil Severcan, Arkadiusz Chworos, Luc Jaeger
Biophysical Journal, 2005, 88, 571a-571a Part 2 Suppl. S
Building Programmable Jigsaw Puzzles with RNA
Arkadiusz Chworos, Isil Severcan, Alexey Y. Koyfman, Patrick Weinkam, Emin Oroudjev, Helen G. Hansma and Luc Jaeger
Science, 2004, 306, 2068-72 (high impact)
https://doi.org/10.1126/science.1104686
Comparison of the cleavage profiles of oligonucleotide duplexes with or without phosphorothioate linkages by using a chemical nuclease probe
Arkadiusz Chworos, Philippe Arnaud , Krystyna Zakrzewska, Piotr Guga, Genevi�ve Pratviel, Wojciech J. Stec and Bernard Meunier
J Biol Inorg Chem., 2004, 9, 374-84
Characterization of the dehydro-guanidinohydantoin oxidation product of guanine in a dinucleotide
Arkadiusz Chworos, Christel Seguy, Genevi�ve Pratviel, and Bernard Meunier
Chem Res Toxicol., 2002, 15, 1643-51
New examples of mixed seleno-sulfides; reactions with triphenylphosphine
Arkadiusz Chworos, Lucyna A. Wozniak and Wojciech J. Stec
Chem Commun., 2002, 7, 518-9
Guanine oxidation: NMR charakterization of a dehydro-guanidinohydantoin residue generated by a 2e-oxidation of d(GpT)
Arkadiusz Chworos, Yannick Coppel, Igor Dubey, Genevieve Pratviel and Bernard Meunier
J.Am.Chem.Soc., 2001, 123, 5867-5877
One-Pot Synthesis of Nucleoside 3-O-(S-Phenyl Methanephosphonothioate)s
Jaroslaw Pyzowski, Arkadiusz Chworos, Lucyna A. Wozniak, Wojciech J. Stec
Tetrahedron Letters, 2000, 41, 1223-1226
Stereochemical Correlation and Absolute Configuration Assignment for Thymidine 3-(S-Phenyl Methanephosphonothioate)
Arkadiusz Chworos and Lucyna A. Wozniak
Proceedings of the 4th Int. Symp. Solid Phase Synthesis & Combinatorial Chemical Libraries York, UK. 1999, entitled „Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries”, 2000, 43-46
The Synthesis of Unsymmetrical S1-(3-O-Thymidine-O-Methanephosphonyl)-S2-p-Nitrophenyl Disulfides and Their Reactions with Triphenylphosphine
Arkadiusz Chworos, Lucyna A. Wozniak and Wojciech J. Stec
Tetrahedron Letters, 2000, 41, 1219-1222
A Facile Conversion of Thio- and Selenophosphoric Acids and Their Derivatives into Fluoridates by Means of Reaction with Silver Fluoride
Arkadiusz Chworos and Lucyna A. Wozniak
Tetrahedron Letters, 1999, 41, 9337-9340
Mixed Phosphorus-Carboxylic Anhydrides as Synthons for Stereoselective Synthesis of [Rp]-Dinucleoside (3,5)-Methanephosphonates
Lucyna A.Wozniak, Arkadiusz Chworos and Wojciech J. Stec
Phosphorus,Sulfur and Silicon; 146, 1999, 649-652
Chemo- and Stereoselectivity of Nucleophilic Substitution at Phosphorus in Mixed Phosphorus-Carboxylic Anhydrides
Lucyna A.Wozniak, Arkadiusz Chworos and Wojciech J. Stec
Phosphorus,Sulfur and Silicon, 1999, 147, 1263-1264
Stereoselective Synthesis of [Rp]-Dinucleoside (3,5)-Methanephosphonates
Lucyna A.Wozniak, Arkadiusz Chworos and Wojciech J. Stec
Phosphorus,Sulfur and Silicon, 1999, 147, 1265-1266
Base-Dependent Regioselective and P-stereocontrolled Hydrolysis of Nucleoside 3-O-(O-2,4,6,-trimethylbenzoyl methanephosphonothioate)s
Lucyna A.Wozniak, Jaroslaw Pyzowski, Arkadiusz Chworos and Wojciech J. Stec
J.Org.Chem., 1998, 63, 9109-9112
Kierownik
Doktorzy
Doktoranci
mgr Sepideh Jafari
Alumni
mgr Justyna Basak
dr inż. Anna Graczyk
dr inż. Rafał Madaj
dr inż. Dominika Jędrzejczyk
dr Justyna Suwara
dr Paulina Gwoździńska
dr Katarzyna Wójcik
mgr Katarzyna Szymańska
mgr Dorota Kuc
mgr Paulina Grzelak
