Education and scientific degrees:
2021 Professor in Chemical Sciences in the field of Biochemistry awarded by the President of Poland
2014 Habilitation degree in Chemical Sciences in the field of Chemistry was awarded by the Center for Molecular and Macromolecular Sciences, Polish Academy of Sciences on June 23, 2014 on the basis of the assessment of scientific achievements entitled ‘Rational design of RNA self-assembly fragments’
2001 Doctor degree in Chemical Sciences in the field of Bioorganic Chemistry was awarded by the Center for Molecular and Macromolecular Sciences, Polish Academy of Sciences on December 10, 2001 on the basis of a dissertation entitled ‘Synthesis and transformation of nucleoside derivatives of methanophosphonic acid and its thio- and selenophosphonyl analogues‘
1996 Master of Science: Lodz University, Department of Mathematics, Physics and Chemistry,
Research experience and interest:
Current and past appointments at the scientific institutions:
2015 – 2023 Deputy Director for Science at the Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences (two terms)
2022 – present Head of the Division of Bioorganic Chemistry at the Centre of Molecular and Macromolecular Studies
2022 – present Professor at the Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences,
2016 – 2022 associate professor at the Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences,
2010 – 2016 adjunct and group leader at the Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences,
2008 – 2009 Senior Researcher at the Department of Chemistry and Biochemistry and Institute for Collaborative Biotechnologies at UC Santa Barbara
2006 – 2008 Project Scientist and Principle Investigator at Physics Department, UC Santa Barbara.
2003 – 2006 Post-graduate Researcher (Level IX) at the Department of Chemistry and Biochemistry and Materials Research Laboratory, UC Santa Barbara with Prof. Luc Jaeger.
2001 – 2002 Post-doctoral associate at Laboratoire de Chimie de Coordination du CNRS, Toulouse, France with Dr. Bernard Meunier.
1995 – 2005 assistant at the Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences,
Short term internships in scientific institutions:
2019 (3 weeks) visiting professor, Faculty of Science, Kasetsart University, Bangkok, Thailand.
2018 (1 month) visiting professor, Faculty of Science, Kasetsart University, Bangkok, Thailand.
2015 (1 week) scientific visit, Faculty of Science, Lund University, Lund, Sweden.
2012 (6 months) visiting professor, Department of Chemistry and Biochemistry, University California, Santa Barbara.
2003 – 2006 post-doctoral stay, Department of Chemistry and Biochemistry, University California, Santa Barbara with Prof. Luc Jaeger.
2001 – 2002 (6 months) post-doctoral stay, Laboratoire de Chimie de Coordination du CNRS, Toulouse, France with Dr. Bernard Meunier.
1999 – 2000 (6 months) scientific internship in the frame of European Associated Laboratory (LEA), Laboratoire de Chimie de Coordination du CNRS, Toulouse, France.
Supervision of students applying for the PhD degree:
Anna Graczyk – PhD thesis: ‘Structural RNA conjugated with gold nanoparticles as a tool for gene expression regulation’, defended with distinctions in 2022. Awarded by the Scientific Council at Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences October 3rd 2022. Function of supervisor.
Dominika Jedrzejczyk – PhD thesis: ‘Structurally defined RNA nanoparticles for gene expression regulation’, defended with distinctions in 2018. Awarded by the Scientific Council at Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences October 15th 2018. Function of supervisor.
Justyna Milczarek – PhD thesis: ‘Conjugated oligoelectrolytes as a fluorescent dyes for staining cell membranes’, defended with distinctions in 2018. Awarded by the Scientific Council at Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences June 18th 2018. Function of supervisor.
Supervision of students applying for the professional engineer or master’s degree:
Katarzyna Wojcik – master’s degree: ‘Enzymatic resistance of RNA tertiary and quaternary structures with three way junctions motif’, defended in 2011 at the Faculty of Food Science and Biotechnology at Technical University of Lodz with distinction.
Paulina Grzelak – master’s degree: ‘Synthesis and biological applications of modified nucleoside triphosphates’, defended in 2012 at the Institute of Organic Chemistry at University of Lodz.
Anna Graczyk – engineer degree: ‘Complex of tRNA with cytochrome C in gel analysis studies’, defended in 2014 at the Faculty of Food Science and Biotechnology at Technical University of Lodz with distinction.
Dominika Jedrzejczyk – master’s degree: ‘Computational investigation of tRNA analogues-cytochrome c complex structures, defended in 2015 at Chemistry Department at Technical University of Lodz.
Katarzyna Szymanska – engineer degree: ‘Colocalization of phenylenevinylene conjugated oligoelectrolytes with commercially available membrane staining dyes in the model mammalian cell system, defended in 2015 at International Faculty of Engineering (IFE), Technical University of Lodz.
Membership in organizations and scientific societies:
2020 – 2023 Member of Chemistry Committee at Polish Academy of Science
2012 – 2018 Editor in Chief for DNA and RNA Nanotechnology Journal (DeGruyter Publisher)
2019 – present Member of Polish Chemical Society
2019 – 2024 Board member of Lodz Division of Polish Chemical Society
2017 – present Member of International Society of RNA Nanotechnology and Nanomedicine (ISRNN)
2015 – 2020 Member of Chemical-Biological-Medical Commission (Polish Academy of Sciences)
1999 – 2015 Member of American Chemical Society (ACS).
2004 – 2015 Member of Biophysical Society
2005 – 2015 Member of American Institute of Chemical Engineers (AIChE)
Projects financed through national and international competitions:
NCN grant (2015/19/B/ST5/03087), title: “Tecto-RNA nano-structures for gene expression regulation in a model system”, 2016 – 2020, in progress, Principal Investigator.
NCN grant (2012/05/B/ST5/00364), title: “Phenylenevinylene oligoelectrolytes for cellular membrane staining”, 2013 – 2016, completed, Principal Investigator.
NCN grant (2011/01/B/NZ3/02090), title: “The tRNA/cytochrome C complex formation and its role in programmed cell death”, 2011 – 2014, completed, Principal Investigator.
MNiSW grant (N302/643740), “Resistance of RNA fragments against nucleases”, 2010 – 2013, completed, Principal Investigator.
NSF grant (0236093), title: “New Applications for Probe Microscopy of Biomolecular Materials”, 2007 – 2008, completed, Principal Investigator.
NSF grant (0520415), “MRSEC: Materials Research Science and Engineering Center”, 2005 – 2012, completed, Senior Researcher.
NIH grant (7802308), title: “Exploring the RNA syntax for engineering therapeutic RNA-based nano-factories”, 2007 – 2012, completed, Senior Researcher.
KBN grant (T09A 061 17), title “Synthesis and reactivity of mixed anhydrides methylphosphonate-carboxylate and its applications for synthesis of oligonucleotide analogues”, 1999 – 2001, PhD scholarship, completed, Principal Investigator.
Membership in the teams assessing applications for financing:
Member of evaluation boards for projects from Ministry of Science and Higher Education in Poland (NAWA, RID), National Centre for Research and Development, National Science Center (NZ – Life Sciences and ST – Physical Sciences and Engineering).
Participation in organizational and scientific committees:
Gordon Research Conferences, RNA nanotechnology, January 13-18, 2017, Ventura, CA – Panel member at Gordon Research Seminar preceding GRC
BIT’s Annual World Congress of Molecular & Cell Biology, Dalian, April 25-28, 2014 – Section Chair
Recent Advances in Nucleic Acid Therapeutics, Lodz, October 15-16, 2015 – conference co-organiser
Papers:
71. Application of 1-Hydroxy-4,5-Dimethyl-Imidazole 3-Oxide as Coformer in Formation of Pharmaceutical Cocrystals, Aneta Wróblewska, Justyna Śniechowska, Sławomir Kaźmierski, Ewelina Wielgus, Grzegorz D. Bujacz, Grzegorz Mlostoń, Arkadiusz Chworos, Justyna Suwara and Marek J. Potrzebowski,
Pharmaceutics, 2020, 12, 359 (Q1, IF2018=4.773, MNiSW=100), doi:10.3390/pharmaceutics12040359
70. DNA:chitosan complex, known as a drug delivery system, can create a porous scaffold, Pitchaya Pakornpadungsit, Thridsawan Prasopdee, Napachanok Mongkoldhumrongkul Swainson, Arkadiusz Chworos, Wirasak Smitthipong,
Polymer Testing, 2020, 83, 106333 (Q1, IF2018=2.943, MNiSW=100), doi.org/10.1016/j.polymertesting.2020.106333
69. Highly Fluorescent Distyrylnaphthalene Derivatives as a Tool for Visualization of Cellular Membranes, Justyna Suwara, Beata Lukasik, Remigiusz Zurawinski, Roza Pawlowska and Arkadiusz Chworos,
Materials, 2020, 13(4), 951, 1-20 (Q2, IF2018=2.972, MNiSW=140), doi:10.3390/ma13040951
68. Noncovalent sericin/chitosan scaffold: physical properties and low cytotoxicity effect, Rungsima Chollakup, Pimporn Uttayarat, Arkadiusz Chworos, Wirasak Smitthipong,
Int. J. Mol. Sci., 2020, 21(3), 775 (Q2, IF2018=4.183, MNiSW=100), doi.org/10.3390/ijms21030775
67. Gold Nanoparticles in Conjunction with Nucleic Acids as a Modern Molecular System for Cellular Delivery, Anna Graczyk, Roza Pawlowska, Dominika Jedrzejczyk and Arkadiusz Chworos, Molecules, 2020, 25, 204, 1-27, (Q2, IF2018=3.06, MNiSW=100), doi.org/10.3390/molecules25010204
66. Multicomponent Conjugates of Anticancer Drugs and Monoclonal Antibody with PAMAM Dendrimers to Increase Efficacy of HER-2 Positive Breast Cancer Therapy, Monika Marcinkowska, Maciej Stanczyk, Anna Janaszewska, Ewelina Sobierajska, Arkadiusz Chworos, Barbara Klajnert-Maculewicz,
Pharmaceutical Research, 2019, 36(11), 154 (Q1, IF2018=3.896, MNiSW=70), doi.org/10.1007/s11095-019-2683-7
65. Theoretical and experimental study on the effects of pH and surfactant on the internal charge transfer process in distyrylnaphthalene-based conjugated oligoelectrolytes, Agnieszka Kowalska-Baron, Remigiusz Zurawinski, Beata Lukasik, Arkadiusz Chworos, Malgorzata Przybyt, Spectrochimica Acta Part A, 2019, 216, 221–229, (Qx, IF2018=2.931, MNiSW=100) doi.org/10.1016/j.saa.2019.03.037
64. RNA Trimeric Nanoparticle for Gene Expression Regulating in a Model GFP System, Dominika J. Jedrzejczyk and Arkadiusz Chworos,
ACS Synthetic Biology, 2019, 8(3), 491-497 (Q1, IF2018=5.571, MNiSW=140), doi:10.1021/acssynbio.8b00319
63. Conjugate of PAMAM Dendrimer, Doxorubicin and Monoclonal Antibody—Trastuzumab: The New Approach of a Well-Known Strategy, Monika Marcinkowska, Ewelina Sobierajska, Maciej Stanczyk, Anna Janaszewska, Arkadiusz Chworos, Barbara Klajnert-Maculewicz
Polymers, 2018, 10(2), 187, 1-11
62. Self-assembly nucleic acid-based biopolymers: learn from the nature, Pitchaya Pakornpadungsit, Wirasak Smitthipong, Arkadiusz Chworos
Journal of Polymer Research, 2018, 25(45), 1-9
61. Theoretical and experimental study on the electronic structure of distyrylnaphtalene-based conjugated oligoelectrolytes, Agnieszka Kowalska-Baron, Remigiusz Zurawinski, Arkadiusz Chworos and Stanislaw Wysocki
Journal of Luminescence, 2018, 196, 81-89
60. Composing RNA nanostructures from a syntax of RNA structural modules, Cody Geary, Arkadiusz Chworos, Erik Verzemnieks, Neil R. Voss and Luc Jaeger,
Nano Letters, 2017, 17 (11), 7095–7101
59. Solvent effects on the photophysical properties of distyrylnaphthalene-based conjugated oligoelectrolytes, Agnieszka Kowalska-Baron, Remigiusz Zurawinski, Beata Lukasik, Arkadiusz Chworos, Stanislaw Wysocki,
Journal of Luminescence, 2017, 192, 359-370
58. Supported Fluid Lipid Bilayer as a Scaffold to Direct Assembly of RNA Nanostructures, Aleksandra P. Dabkowska, Agnes Michanek, Luc Jaeger, Arkadiusz Chworos, Tommy Nylander, Emma Sparr,
Methods Mol Biol., 2017, 1632, 107-122
57. Facile synthesis of fluorescent distyrylnaphthalene derivatives for bioapplications,
Beata Lukasik, Justyna Mielczarek, Roza Pawlowska, Remigiusz Zurawinski and Arkadiusz Chworos, New J. Chem., 2017, 41, 6977-6980
56. Limitations of the fluorescent probes, Justyna Milczarek and Arkadiusz Chworos,
Na pograniczu Chemii i Biologii XXXVI. 2017, 231-240
55. Fluorescence and confocal imaging of mammalian cells using conjugated oligoelectrolytes with phenylenevinylene core, Justyna Milczarek, Roza Pawlowska, Remigiusz Zurawinski, Beata Lukasik, Logan E. Garner and Arkadiusz Chworos,
J. Photochem. & Photobiol., B: Biology 170, 2017, 40–48
54. Designing synthetic RNA for Delivery by Nanoparticles, Dominika Jedrzejczyk, Edyta Gendaszewska-Darmach, Roza Pawlowska, Arkadiusz Chworos,
J. Phys.: Condens. Matter 29, 2017, 123001 1-26
53. RNA Model Evaluation Based on MD Simulation of Four tRNA Analogs, Anna Grzybkowska, Dominika Jędrzejczyk, Michał Rostkowski, Arkadiusz Chworos, Agnieszka Dybala-Defratyka,
RSC Advances 2016, 6, 101778-101789
52. RNA fragments mimicking tRNA analogs interact with cytochrome c, Roza Pawlowska, Magdalena Janicka, Dominika Jedrzejczyk, Arkadiusz Chworos,
Molecular Biology Reports 2016, 43(4), 295-304
51. The α-thio and/or β-γ-hypophosphate Analogs of ATP as Cofactors of T4 DNA Ligase, Roza Pawlowska, Dariusz Korczynski, Barbara Nawrot, Wojciech J. Stec and Arkadiusz Chworos, Bioorganic Chemistry, 2016, 67, 110–115
50. Structural identification of the novel 3 way-junction motif, Dominika Jedrzejczyk and Arkadiusz Chworos, DNA and RNA Nanotechnology, 2015, 2, 35-40
49. The Uptake of Extracellular Vesicles is Affected by the Differentiation Status of Myeloid Cells Czernek Liliana, Chworos Arkadiusz, Duechler Marcus, Scandinavian Journal of Immunology, 2015, 82 (6), 506-514
48. Assembly of RNA nanostructures on supported lipid bilayers, Aleksandra P. Dabkowska, Agnes Michanek, Luc Jaeger, Michael Rabe, Arkadiusz Chworos, Fredrik Hook, Tommy Nylande, Emma Sparr, Nanoscale, 2015, 7(2), 583-596
47. Bio-inspired nucleic acids based materials, Arkadiusz Chworos and Wirasak Smitthipong, Bio-Based Composites for High-Performance Materials: From Strategy to Industrial Application, CRC Press, Taylor & Francis, 2014, chapter 2
46. Phenylenevinylene Conjugated Oligoelectrolytes as Fluorescent Dyes for Mammalian Cell Imaging, Paulina Gwozdzinska, Roza Pawlowska, Justyna Milczarek, Logan E. Garner, Alexander W. Thomas, Guillermo C. Bazan and Arkadiusz Chworos, Chem. Comm. 2014, 50 (94), 14859-14861
45. Cytochrome c interaction with tRNA, the new properties of the known molecules, Roza Pawlowska, Dominika Jedrzejczyk, Magdalena Janicka, Anna Graczyk and Arkadiusz Chworos, Acta Biochimica Polonica, S1, P7.35, 2014, 155
44. DNA-functionalized polystyrene particles and their controlled self-assembly, Rungsima Chollakup, Wirasak Smitthipong and Arkadiusz Chworos, RSC Adv., 4, 2014, 30648–30653
43. Structural analogs of tRNA form a Complex with Cytochrome C, Roza Pawlowska, Dominika Jedrzejczyk, Magdalena Janicka and Arkadiusz Chworos, FEBS Journal, 281, S1, 2014, 398
42. The Complex of tRNA with Cytochrome C in Gel Studies, Anna Graczyk, Dominika Jedrzejczyk, Roza Pawlowska and Arkadiusz Chworos, Collection Symposium Series, 2014, 14, 283-284
41. Rational design of RNA nanoparticles and nanoarrays, Arkadiusz Chworos, RNA Nanotechnologies, Pan Stanford Publishing, 2014, chapter 11, 213-234
40. RNA nanoparticles for gene expression regulation, Roza Pawlowska, Paulina Gwozdzinska and Arkadiusz Chworos, Nucleic Acids Nanotechnologies in Medicine: Diagnosis and Treatment of Diseases, Springer, 2013, chapter 11, 263-290
39. Supramolecular cooperative-assembly of polyelectrolyte films, Rungsima Chollakup, Wirasak Smitthipong and Arkadiusz Chworos, RSC Advances, 2013, 3, 4745-4749.
38. Distyrylbenzene oligoelectrolyte (DSBN+) for human cervical carcinoma cells imaging, Roza Pawlowska, Paulina Gwozdzinska, Logan Garner and Arkadiusz Chworos, MRS Symposium Proceedings, Cambridge University Press, 2013, vol. 1569
37. From Bioorganic Chemistry to Chemical Biology (Od chemii bioorganicznej do biologii chemicznej), Wojciech T. Markiewicz, Henryk Koroniak, Arkadiusz Chworos, Piotr Mucha, Jan Barciszewski, Misja Nauk Chemicznych, Wydawnictwo Nauka I Innowacja, 2011, 109-124.
36. Effect of the Peptide Secondary Structure on the Peptide Amphiphile Supramolecular Structure and Interactions, Dimitris Missirlis, Arkadiusz Chworos, Caroline J. Fu, Htet A. Khant, Daniel V. Krogstad, Matthew Tirrell, Langmuir, 2011, 27, 6163–6170
35. Self-Assembly of an Optically Active Conjugated Oligoelectrolyte, Julia H. Ortony, Tirtha Chatterjee, Logan E. Garner, Arkadiusz Chworos, Alexander Mikhailovsky, Edward J. Kramer Guillermo C. Bazan, Journal of the American Chemical Society, 2011, 133, 8380–8387
34. Promoting RNA Helical Stacking via A-minor Junctions, Cody Geary, Arkadiusz Chworos, Luc Jaeger, Nucleic Acids Research, 2011, 39(2), 1066–1080
33. Self-Assembling RNA Nanorings Based on RNAI/II Inverse Kissing Complexes, Wade W. Grabow, Paul Zakrevsky, Kirill Afonin, Arkadiusz Chworos, Bruce A. Shapiro, Luc Jaeger, Nano Letters, 2011, 11(2), 878–887
32. Improved isolation of proteins tagged with glutathione S-transferase, Nicholas K. Vinckier, Arkadiusz Chworos, Stanley M. Parsons, Protein Expression And Purification, 2011, 75(2), 161-164
31. A polyhedron made of tRNAs, Isil Severcan, Cody Geary, Arkadiusz Chworos, Neil Voss, Erica Jacovetty, Luc Jaeger, Nature Chemistry, 2010, 2, 772 – 779
30. Modification of the Optoelectronic Properties of Membranes via Insertion of Amphiphilic Phenylenevinylene Oligoelectrolytes, Logan E. Garner, Juhyun Park, Scott M. Dyar, Arkadiusz Chworos, James J. Sumner, Guillermo C. Bazan, Journal of the American Chemical Society, 2010, 132 (29), 10042–10052
29. Identification of Bacteria by Conjugated Oligoelectrolyte/Single-Stranded DNA Electrostatic Complexes, Aidee Duarte, Arkadiusz Chworos, Suvi F. Flagan, Grady Hanrahan, Guillermo C. Bazan, Journal of the American Chemical Society, 2010, 132 (36), 12562–12564
28. Specific interaction of DNA-functionalized polymer colloids, Rungsima Chollakup, Wirasak Smitthipong and Arkadiusz Chworos, Polymer Chemistry, 2010, 1 (5), 658-662.
27. A Tripod Molecular Tip for Single Molecule Ligand−Receptor Force Spectroscopy by AFM, Michael E. Drew, Arkadiusz Chworos, Emin Oroudjev, Helen Hansma, Yoko Yamakoshi, Langmuir, 2010, 26 (10), 7117–7125.
26. Automatic Analysis of Conjugated Polyelectrolytes – DNA Interactions Based on Sequential Analysis of AFM Imaging, Arkadiusz Chworos, Boguslaw Obara, IEEE Transactions on Nanotechnology, 8, 2009, 457-462.
25. Square-Shaped RNA Particles from Different RNA Folds, Isil Severcan, Cody Geary, Erik Verzemnieks, Arkadiusz Chworos, and Luc Jaeger, Nano Letters, 9, 2009, 1270-1277.
24. Preliminary structural investigations of the Eut-L shell protein of the ethanolamine ammonia-lyase metabolosome of Escherichia coli, Kiel Nikolakakis, Akashi Ohtaki, Keith Newton, Arkadiusz Chworos and Martin Sagermann, Acta Crystallographica, 65, 2009, F65, Part 2, 128–132
23. Noncovalent Supramolecular Self-assembling Polyelectrolyte: Nucleic Acid Based Materials, Wirasak Smitthipong, Thorsten Neumann, Surekha Gajria, Youli Li, Arkadiusz Chworos, Luc Jaeger, Matthew Tirrell, BioMacromolecules, 2009, 10, 221–228
22. Anatomy and Growth Characteristics of Conjugated Polyelectrolyte/DNA Aggregates, Chunyan Chi, Arkadiusz Chworos, Jinping Zhang, Alexander Mikhailovsky and Guillermo C. Bazan, Advanced Functional Materials, 18, 2008, 3606–3612.
21. Supramolecular Materials Comprising Nucleic Acid Biopolymers, Wirasak Smitthipong, Thorsten Neumann, Arkadiusz Chworos, Luc Jaeger, Matthew Tirrell, Macromolecular Symposia, 264, 2008, 13–17.
20. Self-assembled Materials Containing Complementary Nucleobase Molecular Recognition, Wirasak Smitthipong, Arkadiusz Chworos, Brian Lin, Thorsten Neumann, Surekha Gajria, Luc Jaeger and Matthew Tirrell, Materials Research Society Symposium Proceedings, 1094, 2008.
19. Nucleic acid foldamers: design, engineering and selection of programmable bio-materials with recognition, catalytic and self-assembly properties, Arkadiusz Chworos and Luc Jaeger, Foldamer, by Wiley, Chapter 10, 2007, 291-329.
18. The design and characterization of modular polyhedral architectures made of RNA, Isil Severcan, Cody Geary, Arkadiusz Chworos, Luc Jaeger, Biophysical Journal, 2007 350a-351a Supplement S
17. The architectonics of programmable RNA and DNA nanostructures, Luc Jaeger and Arkadiusz Chworos, Current Opinion of Structural Biology, 16, 2006, 531-543.
16. Thermal stability analysis of self-assembling tRNA tecto-squares, Isil Severcan, Arkadiusz Chworos, Luc Jaeger, Biophysical Journal 88, 2005, 571a Part 2 Supplement S.
15. Controlled Spacing of Cationic Gold Nanoparticles by Nanocrown RNA, Alexey Y. Koyfman, Gary Braun, Sergei Magonov, Arkadiusz Chworos, Norbert O. Reich, Luc Jaeger, Journal of the American Chemical Society, 127, 2005, 11886 -11887
14. From RNA Tectonics to Programmable Jigsaw Puzzles Made of RNA, Arkadiusz Chworos and Luc Jaeger, Proceedings Foundations of Nanoscience, 2005, 157-162
13. Building Programmable Jigsaw Puzzles with RNA, Arkadiusz Chworos, Isil Severcan, Alexey Y. Koyfman, Patrick Weinkam, Emin Oroudjev, Helen G. Hansma and Luc Jaeger, Science, 306, 2004, 2068-2072.
12. Comparison of the cleavage profiles of oligonucleotide duplexes with or without phosphorothioate linkages by using a chemical nuclease probe, Arkadiusz Chworos, Philippe Arnaud , Krystyna Zakrzewska, Piotr Guga, Geneviève Pratviel, Wojciech J. Stec and Bernard Meunier, Journal of Biological Inorganic Chemistry, 9, 2004, 374-384.
11. New examples of mixed seleno-sulfides; reactions with triphenylphosphine, Arkadiusz Chworos, Lucyna A. Wozniak and Wojciech J. Stec, Chemistry Commun.; 7, 2002, 518-519.
10. Characterization of the dehydro-guanidinohydantoin oxidation product of guanine in a dinucleotide, Arkadiusz Chworos, Christel Seguy, Genevieve Pratviel, and Bernard Meunier, Chemical Research in Toxicology; 15, 2002, 1643-1651.
9. Guanine oxidation: NMR characterization of a dehydro-guanidinohydantoin residue generated by a 2e-oxidation of d(GpT), Arkadiusz Chworos, Yannick Coppel, Igor Dubey, Genevieve Pratviel and Bernard Meunier, Journal of the American Chemical Society; 123, 2001, 5867-5877.
8. Stereochemical Correlation and Absolute Configuration Assignment for Thymidine 3’-(S-Phenyl Methanephosphonothioate), Arkadiusz Chworos and Lucyna A. Woźniak, Proceedings of the VIth Int. Symp. Solid Phase Synthesis & Combinatorial Chemical Libraries York, UK. 1999, entitled, Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries 2000; 43-46.
7. The Synthesis of Unsymmetrical S1-(3’-O-Thymidine-O-Methanephosphonyl)-S2-p-Nitrophenyl Disulfides and Their Reactions with Triphenylphosphine, Arkadiusz Chworos, Lucyna A. Woźniak and Wojciech J. Stec, Tetrahedron Letters, 41, 2000, 1219-1222.
6. One-Pot Synthesis of Nucleoside 3’-O-(S-Phenyl Methanephosphono¬thioate)s, Jarosław Pyzowski, Arkadiusz Chworos, Lucyna A. Woźniak, Wojciech J. Stec, Tetrahedron Letters, 41, 2000, 1223-1226.
5. Stereoselective Synthesis of [Rp]-Dinucleoside (3’,5’)-Methanephosphonates, Lucyna A.Woźniak, Arkadiusz Chworos and Wojciech J. Stec, Phosphorus, Sulfur and Silicon; 147, 1999, 1265-1266.
4. Chemo- and Stereoselectivity of Nucleophilic Substitution at Phosphorus in Mixed Phosphorus-Carboxylic Anhydrides, Lucyna A.Woźniak, Arkadiusz Chworos and Wojciech J. Stec, Phosphorus, Sulfur and Silicon; 147, 1999, 1263-1264.
3. Mixed Phosphorus-Carboxylic Anhydrides as Synthons for Stereoselective Synthesis of [Rp]-Dinucleoside (3’,5’)-Methanephosphonates, Lucyna A.Woźniak, Arkadiusz Chworos and Wojciech J. Stec, Phosphorus, Sulfur and Silicon; 146, 1999, 649-652.
2. A Facile Conversion of Thio- and Selenophosphoric Acids and Their Derivatives into Fluoridates by Means of Reaction with Silver Fluoride, Arkadiusz Chworos and Lucyna A. Woźniak, Tetrahedron Letters; 41, 1999, 9337-9340.
1. Base-Dependent Regioselective and P-stereocontrolled Hydrolysis of Nucleoside 3′-O-(O-2,4,6,-trimethylbenzoyl methanephosphonothioate)s, Lucyna A.Woźniak, Jaroslaw Pyzowski, Arkadiusz Chworos and Wojciech J. Stec, Journal of Organic Chemistry; 63, 1998, 9109-9112.
