dr hab. Beata Miksa

Adiunkt, Dział Chemii Strukturalnej

Telefon: (+48) (42) 68 03 209

Email:

Education

• Post-doctoral thesis: “Synthesis of fluorescent nanocarriers for an anticancer therapy dedicated to optical molecular imaging methods” proceeded in Centre of Molecular and Macromolecular Studies of the Polish Academy of Science, Lodz, Department of Structural Chemistry, Poland, 2019
• Postdoc: The University of Memphis, Department of Chemistry, Memphis TN, USA, 2007-2008
• Postdoc: Kansas State University, Department of Chemistry, Manhattan, USA, 2006-2007
• Dr.: Centre of Molecular and Macromolecular Studies of the Polish Academy of Science, Lodz, Institute of Polymer Chemistry, Poland, 2005

Research Focus

Making biomimetic polymer nanocapsules with new and superior properties to address current problems in medical imaging and treatment, diagnostic systems for an anticancer therapy.

Current Publications

• Andrzej Błauż,  Błażej Rychlik, Damian Plażuk, Francesca Peccati, Gonzalo Jimenez-Oses, Urszula Steinke, Malgorzata Sierant,
  Katarzyna Trzeciak, Ewa Skorupskad and Beata Miksa * Biotin-phenosafranin as a new photosensitive
  conjugate for targeted therapy and imaging, New J. Chem., 2021, DOI: 10.1039/d0nj06170k
• Beata Miksa,* Urszula Steinke, Katarzyna Trzeciak, Justyna Sniechowska, and Artur Rozanski Thermostable Fluorescent Capsules with the Cross-Linked Heterocyclic Polymer Shell from Poly(pyrrole-phenosafranin), Macromolecular Chemistry and Physics 2021, DOI: 10.1002/macp.202000396
• Rozga-Wijas, M. Sierant, E. Wielgus, B. J. Miksa. Polyhedral octasilsesquioxanes labelled with the photosensitive cationic phenosafranin dye as a new nanocarrier for therapy and cellular imaging, Dyes and Pigments 2019, 161, 261-266. (IF = 3.7)
• Miksa, M. Sierant, E. Skorupska, A. Michalski, S. Kaźmierski, U. Steinke, A. Różański, P. Uznański. Chlorambucil labelled with the phenosafranin scaffold as a new chemotherapeutic for imaging and cancer treatment , Colloids and Surface B: Biointerfaces 2017, 159,  820-828. (IF = 4.2)
• Miksa B. Fluorescent Dyes Used in Polymer Carriers as Imaging Agents in Anticancer Therapy, Medicinal Chemistry (Los Ageles), 2016, 6, 611-639, doi:10.4172/2161-0444.1000406. (open access IF = 1.9 in scholar citation index, the most view article 10368 times).
• Miksa B. Recent progress in shell cross-linked polymer capsules for drug delivery, RSC Advances, 2015, 5, 87781-87805. (IF=3.840)
• Sierant M., Kazmierski S., Rozansli A., Paluch P., Bienias U., Miksa B. J. Nanocapsules for 5-fluorouracil delivery decorated with a poly(2-ethylhexyl methacrylate-co-7(4-trifluoromethyl)coumarin acrylamide) cross-linked wall, New Journal of Chemistry, 2015, 39, 1506-1516. (IF=3.2)
• Sierant M., Paluch P. Florczak M., Rozanski A., Miksa B. Photosensitive nanocapsules for use in imaging from poly(styrene-co-divinylbenzene) cross-linked with coumarin derivatives, Colloids and Surfaces B: Biointerfaces, 2013, 111, 571-578. (IF=4.2)
• Miksa B. J., Sochacki M., Sroka-Bartnicka A., Uznanski P., Nosal A., Potrzebowski M. J. Application of parylene for Surface (polimer) enhanced laser desorption/ionization of synthetic polymer, Rapid Communications in Mass Spectrometry, 2013, 27, 767-772. (IF=2.253)
• Miksa B, Sochacki M., Libiszowski J., Duda A., Ciesielski W., Potrzebowski M. Application of ionic liquid matrices in spectra analysis of poly(lactide)-solid state NMR spectroscopy versus matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry, Analytical Methods, 2012, 4, 377-383. (IF = 1.9)
• Potrzebowski M. J., Kazmierski S., Kassassir H., Miksa B. Phosphorus-31 NMR Spectroscopy of Chapter 2-Condensed Matter, Annual Reports on NMR Spectroscopy, 2010, 70, 35-114. (IF=2.273)
• Dergunov S. A., Miksa B., Ganus B., Lindner E., Pinkhassik E. Nanocapsules with invisible walls, Chemical Communications, 2010, 46, 1485-1487. (IF= 6.8)
• Miksa B., Chinnappan R., Dang N. C., Reppert M., Matter B., Tretyakova N., Grubor N. M., Jankowiak R. Spectral Differentiation and Immunoaffinity Capillary Electrophoresis Separation of Enantiomeric Benzo(a)pyrene Diol Epoxide-Derived DNA Adducts, Chemical Research of Toxicology, 2007, 20, 1192-1199. (IF=3.2)
• Patents :

 – PL 222065 B1: Potrzebowski M., Sroka-Bartnicka A., Miksa B., Sochacki M,

                –  B1 (11) 171637 (Wiad. Urz. Pat.): Słomkowski S, Miksa B.

• 2011-2014,  Principal Investigator in grant N N209 62440 (from National Science Centre, Poland) about “The preparation of synthetic liposomes with encapsulated API”.

Experience and technical skills

MALDI-TOF mass spectrometry, Gas chromatography – mass spectrometry, NMR spectroscopy, FTIR spectroscopy,  Fluorescence and UV-vis spectroscopy, Circular Dichroism spectroscopy, Free-Flow Capillary Electrophoresis, Dynamic Light Scattering, Scanning Electron Microscopy