Projekty zrealizowane:
Laboratorium Analizy Mas Cząsteczkowych w Dziale Polimerów świadczy usługi w zakresie oznaczania mas cząsteczkowych, rozrzutu mas cząsteczkowych, itp. parametrów charakteryzujących strukturę makrocząsteczek w roztworze.
Laboratorium dysponuje zestawami chromatograficznymi firmy Agilent, Wyatt oraz Shimadzu do analiz w rozpuszczalnikach organicznych (CH2Cl2 i DMAc, woda). Dysponujemy zestawami chromatograficznymi typu SEC – MALLS (detekcja RI i MALLS). Metody pomiaru pozwalają na oznaczenie rzeczywistych mas cząsteczkowych (detektor MALLS) analizowanych polimerów, oraz względny pomiar mas cząsteczkowych z użyciem kalibracji na PS (detektor RI).
Marta Socka, Małgorzata Baśko, Marek Brzeziński, Bartłomiej Kost
Synthesis and properties of polylactide-graft-poly(methyl methacrylate) copolymers with degradable main backbone
Macromolecules, 2025, 58, 2, 1103–1116
Bartłomiej Kost, Magdalena Słojewska, Małgorzata Baśko, Sławomir Kaźmierski, Ewa Zygadło-Monikowska, Przemysław Kubisa
Polyacetals of higher cyclic formals. Synthesis, properties and application as polymer electrolytes
Polymer Chemistry, 2025,16, 598-608
Hoelm Marta, Wzgarda-Raj Kinga, Kinart Zdzisław, Kost Bartłomiej, Brzezinski Marek , Staniec Paulina
Synthesis, crystal structure elucidation, theoretical characterization and thermochemistry analysis of the potential anticancer drug BFS
Acta Crystallographic C, 2025
Bartłomiej Kost, Marta Socka, Karolina Cichoń, Marek Brzeziński, Malgorzata Basko, Tadeusz Biela
Molar Mass Determination via Linear Regression from SEC Measurements: The case of Polylactide, Polycaprolactone and Poly(2,2-dimethylthrimethylene carbonate)
Polymers for Advanced Technology 2024
B. N. Vedha Hari, T. Makowski, P. Sowiński, A. Domańska, W. Gonciarz, M. Brzeziński
3D printing of dolutegravir-loaded polylactide filaments as a long-acting implantable system for HIV treatment
International Journal of Biological Macromolecules 2024, 258, 128754
Aneta Kopańska, Marek Brzeziński, Zbigniew Draczyński
Combination of polylactide with cellulose for biomedical applications: a recent overview Cellulose (2024) 31:101–145
Przemysław Kubisa
Synthesis and polymerization of cyclic formals of oligooxyethylene diols
Polym Adv Technol. 2024;35:e6271.
Melania Bedarek, Mateusz Grabowski
Polylactide/poly(vinyl monomer) block copolymers for specific applications
Polymer Reviews, 2024, 64(3), 898–938.
M. Saravanan, B.N. Vedha Hari, Marek Brzeziński, Weronika Gonciarz, I. Vetha Potheher, T. C. Sabari Girisun
Improved antibacterial activity and biocompatibility of porphyrin functionalized metal decorated reduced graphene oxide
Surface and Interfaces 2024, 46, 103932
Weronika Gonciarz, Marek Brzeziński, Weronika Orłowska, Paweł Wawrzyniak, Artur Lewandowski, Vedha Hari B. N., Magdalena Chmiela
Spray‑dried pH‑sensitive chitosan microparticles loaded with Mycobacterium bovis BCG intended for supporting treatment of Helicobacter pylori infection
Scientific Reports 2024, 14, 4747
Priya Dharshini Krishnan, Ramya Devi Durai, Sivanjineyulu Veluri, Vedha Hari B Narayanan
Semisolid extrusion 3D printing of Dolutegravir-Chitosan nanoparticles laden polymeric buccal films: personalized solution for pediatric treatment Biomed. Mater. 2024, 19, 025046
Aneta Kopańska, Marek Brzeziński, Weronika Gonciarz, Zbigniew Draczyński
Compatibilizing of cotton fabric with hydrophobic drug cover layer for anti-inflammatory performance with the implementation of ibuprofen
Scientific Reports 2024, 14, 7310
Melania Bednarek, Mateusz Grabowski, Magdalena Lipińska, Andrzej Pawlak
Reversible polymer networks based on polylactide with tetraphenylethane thermally dissociating groups in crosslinks
Polym.Adv. Technol., 2024;35
Bartosz Kopka, Bartłomiej Kost, Andrzej Pawlak, Agata Tomaszewska, Agnieszka Krupa, Malgorzata Basko
Covalent segmented polymer networks composed of poly(2-isopropenyl-2-oxazoline) and selected aliphatic polyesters: designing biocompatible amphiphilic materials containing degradable blocks
Soft Matter, 2023, 19, 6987–6999
Vedha Hari B Narayanan, Bartłomiej Kost, Artur Lewandowski, Ramya Devi Durai, Paweł Wawrzyniak, Tadeusz Biela, Roland Schwarzer, Hannah Sabeth Sperber, Rieke Wingenfeld, Marek Brzeziński
PLA stereocomplex-chitosan nanoparticles loaded with tenofovir alafenamide as a long-acting antiretrovirals
Advanced Powder Technology 2023, 34, 11, 104205
Karolina Cichoń, Irena I. Bak-Sypien, Malgorzata Basko, Bartłomiej Kost
Synthesis and Characterization of Functionalized Polylactides Containing Acetal Units
Macromolecules 2023, 56, 6951−6967,
Weronika Gonciarz, Magdalena Chmiela, Bartłomiej Kost, Ewelina Piątczak, Marek Brzeziński
Stereocomplexed microparticles loaded with Salvia cadmica Bioss. extracts for enhancement of immune response towards Helicobacter pylori
Scientific Reports, (2023), 13, 7039
Marek Brzeziński, Weronika Gonciarz, Bartłomiej Kost, Magdalena Chmiela
Can histamine cause an enhancement of the cellular uptake and cytotoxicity of doxorubicin-loaded polylactide nanoparticles?
European Journal of Pharmaceutical Sciences, (2023), 185, 106438
Bartosz Kopka, Bartłomiej Kost, Julia Wrześniewsk, Katarzyna Rajkowska, Sławomir Kadłubowski, Alina Kunicka-Styczyńska, Andrzej Baryga, Weronika Gonciarz, Malgorzata Basko, Marek Brzeziński
Supramolecular poly(vinyl alcohol)-based hydrogels containing quercetin for bacterial and fungal elimination
European Polymer Journal, (2023), 187, 111881.
Mateusz Grabowski, Bartłomiej Kost, Agnieszka Bodzioch, Melania Bednarek
Functionalization of polylactide with multiple tetraphenyethane infer groups to form PLA block copolymers with vinyl monomers
International Journal of Molecular Sciences, (2023), 24, 19
Agnieszka Kobylińska, Bartłomiej Kost, Karolina Cichoń, Irena Bąk-Sypień, Marek Brzezińśki
Stereocomplexed Microparticles as Quercetin Carriers for Improving Plant Growth During Salinity Stress
Journal of Polymer Environement, (2023), 31, 1209–1220
Karolina Cichoń, Bartłomiej Kost, Malgorzata Basko
Synthesis and properties of ABA-triblock copolymers from polyester A-blocks and easily degradable polyacetal B-blocks
Polymer Chemistry, (2022),13, 5243-5255
2Bartosz Kopka, Bartłomiej Kost, Małgorzata Baśko
Poly (2-isopropenyl-2-oxazoline) as a reactive polymer for materials development
Polymer Chemistry, (2022), : Polym. Chem., 2022, 13, 4736–4746
Bartłomiej Kost, Alina Kunicka-Styczyńska, Aleksandra Plucińska, Katarzyna Rajkowska, Malgorzata Basko, Marek Brzeziński
Microfluidic preparation of antimicrobial microparticles composed of l-lactide/1, 3-dioxolane (co) polymers loaded with quercetin,
Food Chemistry, 369 (2022), 133639.
Bartłomiej Kost, Malgorzata Basko, Melania Bednarek, Marta Socka, Bartosz Kopka, Grzegorz Łapienis, Tadeusz Biela, Przemysław Kubisa, Marek Brzeziński
The influence of the functional end groups on the properties of polylactide-based materials
Progress in Polymer Sciences, 130, (2022), 101556
Mateusz Grabowski, Bartłomiej Kost, Przemysław Kubisa, Melania Bednarek
A New Approach to The Synthesis of Polylactide/Polyacrylonitrile Block Copolymers,
Polymers, 14(8) (2022) 1529
Mateusz Grabowski, Bartłomiej Kost, Bartłomiej Gostyński, Melania Bednarek
Can tetraphenylethane (TPE) “iniferter” groups be introduced into polymer chains by coupling TPE diol with diisocyanates?
Polymer, 246, (2022), 124738
Bartosz Kopka, Bartłomiej Kost, Katarzyna Rajkowska, Andrzej Pawlak, Alina Kunicka-Styczyńska, Tadeusz Biela, Małgorzata Baśko
A simple strategy for efficient preparation of networks based on poly(2-isopropenyl-2-oxazoline), poly(ethylene oxide), and selected biologically active compounds: Novel hydrogels with antibacterial properties
Soft Matter, 16 Nov 2021
Bartłomiej Kost, Weronika Gonciarz, Agnieszka Krupa, Marta Socka, Maciej Rogala, Tadeusz Biela, Marek Brzeziński
pH-Tunable Nanoparticles Composed of Copolymers of Lactide and Allyl-Glycidyl Ether with Various Functionalities for the Efficient Delivery of Anti-Cancer Drugs,
Colloids and Surface B: Biointerfaces, 204 (2021) 111801
Marek Brzeziński, Marta Socka, Tomasz Makowski, Bartłomiej Kost, Marcin Cieślak, Karolina Królewska-Golińska
Microfluidic-assisted nanoprecipitation of biodegradable nanoparticles composed of PTMC/PCL (co) polymers, tannic acid and doxorubicin for cancer treatment,
Colloids and Surfaces B: Biointerfaces, 2021, 201, 111598
P. Dharshini, H. Fang, D. R. Devi, J.-X. Yang, R.-H. Luo, Y.-T. Zheng, M. Brzeziński, B. N. V. Hari
pH-sensitive chitosan nanoparticles loaded with dolutegravir as milk and food admixture for paediatric anti-HIV therapy
Carbohydrate Polymers, 2021, 256, 117440
Svyntkivska, T. Makowski, E. Piorkowska, M. Brzeziński, A. Herc, A. Kowalewska, Modification of Polylactide Nonwovens with Carbon Nanotubes and Ladder Poly(silsesquioxane)
Molecules (Basel, Switzerland), 2021, 26(5), 1353 (1-13)
Bartłomiej Kost, Malgorzata Basko
Synthesis and properties of l-lactide/1, 3-dioxolane copolymers: preparation of polyesters with enhanced acid sensitivity,
Polymer Chemistry, 12 (2021), 2551-2562.
Andrzej Błauż, Błażej Rychlik, Damian Plazuk, Francesca Peccati, Gonzalo Jiménez-Osés, Urszula Steinke, Malgorzata Sierant, Katarzyna Trzeciak, Ewa Skorupska, Beata Miksa
Biotin-phenosafranin as a new photosensitive conjugate for targeted therapy and imaging
New J. Chem., 2021, 45, 9691
Beata Miksa, Urszula Steinke, Katarzyna Trzeciak, Justyna Sniechowska, Artur Rozanski
Thermostable Fluorescent Capsules with the Cross-Linked Heterocyclic Polymer Shell from Poly(pyrrole-phenosafranin)
Macromol. Chem. Phys. 2021, 222, 2000396
Kubisa, G. Lapienis, T. Biela
Star-shaped copolymers with PLA–PEG arms and their potential applications as biomedical materials
Polym. Adv. Technol. 2021; 32, 3857-3866
Klimaszewska, M.; Górska, S.; Łapienis, G.; Kaleta, B.; Górska, S.; Kaszowska, M.; Dawidowski, M.; Gamian, A.; Zagożdżon, R.; Górski, A.; Jadwiga Turło
Identification of the Primary Structure of Selenium-Containing Polysaccharides Selectively Inhibiting T-Cell Proliferation. Molecules 2021, 26, 5404.
Bojda, E. Piorkowska, G. Lapienis, A. Michalski
Shear-Induced Crystallization of Star and Linear Poly(L-lactide)s.
Molecules 2021, 26, 6601.
Melania Bednarek, Katarina Borska, Przemysław Kubisa
New Polylactide-Based Materials by Chemical Crosslinking of PLA
Polymer Reviews 2021, VOL. 61, NO. 3, 493–519
Katarina Borska, Melania Bednarek, Andrzej Pawlak
Reprocessable polylactide-based networks containing urethane and disulfide linkages
European Polymer Journal 156 (2021) 110636
Marek Brzeziński, Bartłomiej Kost, Weronika Gonciarz, Agnieszka Krupa, Marta Socka, Maciej Rogala,
Nanocarriers based on block copolymers of l-proline and lactide: The effect of core crosslinking versus its pH-sensitivity on their cellular uptake.
European Polymer Journal, 156, 5 August 2021, 110572.
Roksana Bernat, Paulina Maksym, Magdalena Tarnacka, Katarzyna Malarz, Anna Mrozek-Wilczkiewicz, Tadeusz Biela, Sylwia Golba, Ewa Kaminska, Marian Paluch, Kamil Kaminski
High pressure as a novel tool for the cationic ROP of γ-butyrolactone
RSC Adv., 2021, 11, 34806
Roksana Bernat, Paulina Maksym, Magdalena Tarnacka, Kajetan Koperwas, Justyna Knapik-Kowalczuk, Katarzyna Malarz, Anna Mrozek-Wilczkiewicz, Andrzej Dzienia, Tadeusz Biela, Roman Turczyn, Luiza Orszulak, Barbara Hachuła, Marian Paluch, Kamil Kamiński
The effect of high-pressure on organocatalyzed ROP of γ-butyrolactone
Polymer Volume 233, 2021, 124166
Kubisa
Kinetics of radical polymerization in ionic liquids
European Polymer Journal 133, 109778 (pp. 1-10) (2020).
Bednarek, K. Borska, P. Kubisa,
Crosslinking of Polylactide by High Energy Irradiation and Photo-Curing
Molecules 25, 4919 (pp. 1-28) (2020).
Socka, A. Michalski, I. M. Pelin, A. Pawlak, F. Tanasa, T. Biela, M. Basko,
Preparation of biomimetic composites of hydroxyapatite and star-shaped poly(2,2-dimethyl trimethylene carbonate)s terminated with carboxyl end-groups
Polymer 186, 122078 (pp. 1-10) (2020).
Kost, M. Svyntkivska, M. Brzeziński, T. Makowski, E. Piorkowska, K. Rajkowska, A. Kunicka-Styczyńska, T. Biela,
PLA/βCD based fibers loaded with quercetin as potential antibacterial dressing materials
Colloids and Surface B: Biointerfaces, 190, 110949 (pp. 1-10) (2020).
Brzeziński, A. Michalski, B. Kost, M. Socka, M. Florczak, G. Łapienis, T. Biela
Simultaneous Stereocomplexation of Polylactides during Polymerization of D-LA in the Presence of a PLLA Template
Macromol. Chem. Phys. 221, 1900571 (pp. 1-6) (2020).
Krajenta, M. Polińska, G. Lapienis, A. Pawlak
The crystallization of poly(ethylene oxide) with limited density of macromolecular entanglements
Polymer 197, 122500 (pp. 1-10) (2020).
Kost, M. Brzeziński, M. Socka, M. Baśko, T. Biela
Biocompatible Polymers Combined with Cyclodextrins: Fascinating Materials for Drug Delivery Applications
Molecules 25, 3404 (pp. 1-44) (2020).
Kost, M. Brzeziński, M. Zimnicka, M. Socka, E. Wielgus, M. Słowianek, T. Biela,
PLA Stereocomplexed Microspheres Modified with Methyl-beta-Cyclodextrinas an Atropine Delivery System. Synthesis and Characterization
Mater. Today Commun. 25, 101605 (pp. 1-11) (2020).
Słowikowska, K. Chajec, A. Michalski, S. Zapotoczny, K. Wolski
Surface-Initiated Photoinduced Iron-Catalyzed Atom Transfer Radical Polymerization with ppm Concentration of FeBr3 under Visible Light
Materials 13, 5139 (pp. 1-17) (2020).
Rubinsztajn, J. Chojnowski, U. Mizerska, M. Basko, P. Uznanski, A. Walkiewicz-Pietrzykowska, M. Cypryk
Reactions of Zirconium (IV) n-Propoxide with SiHFunctional Polysiloxanes as a Route to Siloxane–Zirconium Hybrid Materials with Enhanced Refractive Index
Macromol. Rapid Commun. 41, 2000601 (pp.1-8) (2020).
Piórecka, J. Kurjata, I. Bąk-Sypień, M. Cypryk, U. Steinke, W. A. Stańczyk
Reasons for enhanced activity of doxorubicin on co-delivery with octa(3-aminopropyl)silsesquioxane
RSC Adv., 10, 15579-15585 (2020).
Piórecka, A. Janaszewska, M. Majkowska, M. Marcinkowska, J. Kurjata, S. Kaźmierski, E. Radzikowska-Cieciura, B. Kost, P. Sowiński, B. Klajnert-Maculewicz, W. A. Stańczyk,
Hydrophilic Polyhedral Oligomeric Silsesquioxane, POSS(OH)32, as a Complexing Nanocarrier for Doxorubicin and Daunorubicin
Materials, 13, 5512 (2020).
Łapienis
Ring-Opening Polymerization of Cyclic Phosphorus Monomers.
In: Saleem Hashmi (editor in chief), Reference Module in Materials Science and Materials Engineering. Oxford: Elsevier, 2019, pp. 1–69.
Slomkowski, C.M. Fellows, R.C. Hiorns, R.G. Jones, P. Kubisa, C.K. Luscombe, T. Nakano, G.T. Russell, C.G. Dos Santos, C. Scholz, N. Stingelin, M.G. Walter
List of keywords for polymer science (IUPAC Technical Report)
Pure and Applied Chemistry, 91, 997-1027 (2019).
Michalski, M. Brzezinski, G. Lapienis, T. Biela
Star-shaped and branched polylactides: Synthesis, characterization, and properties
Progress Polymer Sci, 89, 159-212 (2019).
Wojtczak, T. Biedroń, M. Bednarek
Hydrolytic stability of polylactide stereocomplex microparticles containing metal ions
Polymer Bulletin, 76,1135–1149 (2019).
Brzeziński, M. Socka, B. Kost
Microfluidics for producing polylactide nanoparticles and microparticles and their drug delivery application
Polymer International, 68, 997-1014 (2019).
Bednarek, P. Kubisa
Reversible networks of degradable polyesters containing weak covalent bonds
Polymer Chemistry, 10, 1848-1872 (2019).
Kost, M. Brzeziński, M. Cieślak, K. Królewska-Golińska, T. Makowski, M. Socka, T. Biela
Stereocomplexed micelles based on polylactides with β-cyclodextrin core asanti-cancer drug carriers
Europ. Polym. J., 120, 1092712 (2019).
Brzezinski, B. Kost, S. Wedepohl, M. Socka, T. Biela, M. Calderon
Stereocomplexed PLA microspheres: control over morphology, drugencapsulation and anticancer activity
Colloids and Surfaces B: Biointerfaces, 184, 110544 (pp 1-8) (2019).
Socka, M. Sitko, S. Boncel, B. Kost, A. Chrobok, M. Brzeziński,
Nanobiocatalyst from Lipase Non-covalently Immobilized on Multiwalled Carbon Nanotubes for Copolymerization of e-Caprolactone and Trimethylene Carbonate,
Polym. Degrad. Stab., 170, 109000 (pp 1-9) (2019).
Dzienia, P. E. Maksym, B. Hachuła, M. Tarnacka, T. Biela, S. Golba, M. Chorążewski, A. Zięba, K. Kaminski, M. Paluch
Studying catalytic activity of DBU and TBD upon water-initiated ROP of ε-caprolactone at different thermodynamic conditions
Polym. Chem., 10, 6047-6061 (2019).
Danko, P.Hrdlovic, M. Brzezinski, A. Duda, T. Biela
Real-time monitoring of stereocomplex formation of poly(l-lactide) and poly(d-lactide) decorated with pyrene derivative as a fluorescence probe.
Polymer 156, 76–84, 2018
Piechocki, M. Kozanecki, S. Kadłubowski, B. Pacholczyk-Sienicka, P. Ulański, T. Biela
Controlling the properties of radiation-synthesized thermoresponsive oligoether methacrylate hydrogels by varying the monomer side-chain length; self-composite network containing crystalline phase
Polymer, 150, 275-288, 2018
Michalski, M. Brzeziński, P. Kubisa, T. Biela
Supramolecular aggregates of linear and star-shaped polylactides with different numer of hydroxyl or carboxyl end-groups
Reactive and Functional Polymers 128, 67-73, 2018
Puchalski, G. Szparaga, T. Biela, A. Gutowska, S. Sztajnowski, and I. Krucinska
Molecular and Supramolecular Changes in Polybutylene Succinate (PBS) and Polybutylene Succinate Adipate (PBSA) Copolymer during Degradation in Various Environmental Conditions,
Polymers, 10, 251, 2018
Michalski, M. Socka, M. Brzeziński, T. Biela
Reversible supramolecular PLA gels obtained via stereocomplexation
Macromol. Chem. Phys., 1700607, 2018.
Biela, M. Brzeziński,
Supramolecular Interactions, a Route to Control Properties and Interfaces in PLA Based Materials
Curr. Org. Chem. 21, 2466-2478, 2017
Biedroń, A. Michalski, T. Biela, P. Kubisa
Stereocomplexation of polylactides containing ionic liquid end-groups,
Polimery, 62, 254-261, 2017
Biela et. al.
Influence of the homehold composting conditions on the structural changes of polylactide spun-bonded nonwovens during degradation
Textile Research Journal, 87, 2541-2549, 2017
Florczak, A. Michalski, A. Kacprzak, M. Brzeziński, T. Biedroń, A. Pająk, P. Kubisa, T. Biela
MALDI-TOF Analysis of Lactide Oligomers with Functional End Groups
React. Funct. Polym., 104, 71-77, 2016
Biela, M. Brzeziński
Supramolekularne polilaktydy – metody otrzymywania i wybrane właściwości,
Polimery (Warsaw), 61, 397-406, 2016
Michalski, T. Makowski, T. Biedroń, M. Brzeziński and T. Biela
Controlling Polylactide Stereocomplexes (sc-PLA) Self-Assembly: From Microspheres to Nanoparticles
Polymer, 90, 242-248, 2016
Brzeziński, T. Biela
in Encyclopedia of Polymeric Nanomaterials: Stereocomplexed polylactides,
eds. S. Kobayashi and K. Müllen, Springer, Berlin, 2015
Brzeziński, T. Biela,
Supramolecular polylactides by the cooperative interaction of the end groups and stereocomplexation
Macromolecules 48, 2994-3004, 2015
Brzeziński, T. Biela
Micro- and nanostructures of polylactide stereocomplexes and their biomedical applications,
Polym. Int 64, 1667-1675, 2015
Biela, D. Neugebauer
Water soluble well-defined acidic graft copolymers based on a poly(propylene glycol) macromonomer
RSC Advances 5, 3627-3635, 2015
Brzeziński, T. Biedroń, A. Tracz, P. Kubisa, T. Biela
Spontaneous Formation of Colloidal Crystals of PLA Stereocomplex Microspheres and their Hierarchical Structure
Macromol. Chem. Phys. 215, 27-31, 2014
Brzeziński, T. Biela
Polylactide Nanocomposites with functionalized carbon nanotubes and their stereocomplexes: A focused review
Materials Letters 121, 244-250, 2014