Sonata Bis Monika Gosecka

Tytuł projektu: „Hydrożele zbudowane z dynamicznych węzłów o kontrolowanej przepuszczalności i wzmożonej rozpuszczalności leków do potencjalnego leczenia ginekologicznego” (UMO-2018/30/E/ST5/00576)

Kierownik projektu: dr hab. Monika Gosecka

Wykonawcy:
inż. Małgorzata Urbaniak
mgr inż. Daria Jaworska-Krych
mgr inż. Piotr Ziemczonek
dr inż. Mateusz Gosecki
dr inż. Sławomir Kaźmierski

Efekty

1. Gosecka M., Jaworska-Krych D., Gosecki M., Urbaniak M., Wielgus E., Gostynski B., Marcinkowska M., Janaszewska A., Klajnert-Maculewicz B. „Construction of Dynamic Hydrogel Inducing Effective and Selective 5-Fluorouracil Monotherapy against Cervical Cancer Cells” ACS Applied Materials and Interfaces 2024, 17, 13427-13444
2. Jaworska-Krych D., Gosecka M., Maczugowska P., Halagan K., Szutkowski K., Gosecki M., Urbaniak M., Kozanecki M. „Thermosensitive Behavior of Internally Phenyl-Enriched Hyperbranched Polyglycidols in Water-The Influence of a Covalent Bond Used for the Hydrophobization” Macromolecules 2024, 57, 9135-9156
3. Jaworska-Krych D., Gosecka M., Gosecki M., Uraniak M., Dzitko K., Ciesielska A., Wielgus E., Kadlubowski S., Kozanecki M. „Enhanced Solubility and Bioavailability of Clotrimazole in Aqueous Solutions with Hydrophobized Hyperbranched Polyglycidol for Improved Antifungal Activity” ACS Applied Materials and Interfaces 2024, 16, 18434-18448
4. Yin B.H. , Gosecka M., Bodaghi M., Youssef G., Dodda J.M., Wong S.H.D., Bin Imran A., Gosecki M., Jobdeedamrong A., Naniz M.A., Zolfagharian A. “Engineering multifunctional dynamic hydrogel for biomedical and tissue regenerative applications” Chemical Engineering Journal 2024, 487, 150403
5. Gosecka M.*, Gosecki M., Ziemczonek P., Urbaniak M., Wielgus E.; Marcinkowska M.; Janaszewska A.; Klajnert-Maculewicz B. „Selective anti-cervical cancer injectable and self-healable hydrogel platforms constructed of drug-loaded cross-linkable unimolecular micelles in a single and combination therapy” ACS Applied Materials and Interfaces 2024
6. Gosecki M., Urbaniak, M. Urbaniak, Martinho N., Gosecka M.*, Zloh M. “Evaluation of Encapsulation Potential of Selected Star-Hyperbranched Polyglycidol Architectures: Predictive Molecular Dynamics Simulations and Experimental Validation” Molecules 2023, 28, 7308
7. Monika Gosecka*, Mateusz Gosecki, Daria Jaworska-Krych, „Hydrophobized hydrogels: construction strategies, properties, and biomedical applications” Advanced Functional Materials 2023, doi: 10.1002/adfm.202212302, IF=19,924
8. Mateusz Gosecki, Piotr Ziemczonek, Monika Gosecka, Malgorzata Urbaniak, Ewelina Wielgus, Monika Marcinkowska, Anna Janaszewska, Barbara Klajnert-Maculewicz, „Cross-linkable star-hyperbranched unimolecular micelles for the enhancement of the anticancer activity of clotrimazole” Journal of Materials Chemistry B 2023, doi: 10.1039/d2tb02629e, IF=6,788;
9. Blair Brettmann, Marco A. Fraga, Monika Gosecka, Natalie Stingelin “Introduction to Polymer Upcycling” Journal of Materials Chemistry A 2023, doi: 10.1039/d3ta90040a, IF=14,50
10. Monika Gosecka, Daria Jaworska-Krych, Mateusz Gosecki, Ewelina Wielgus, Monika Marcinkowska, Janaszewska, Barbara Klajnert-Maculewicz “Self-Healable, Injectable Hydrogel with Enhanced Clotrimazole Solubilization as a Potential Therapeutic Platform for Gynecology” Biomacromolecules 2022, 22, 4203-42196, IF=7,055;
11. Monika Gosecka, Mateusz Gosecki, Malgorzata Urbaniak, „Composite dynamic hydrogels constructed on boronic ester cross-links with NIR-enhanced diffusivity”. Biomacromolecules 2022; DOI10.1021/acs.biomac.1c01359. IF=7,055;
12. Monika Gosecka, Mateusz Gosecki, „Antimicrobial Polymer-Based Hydrogels for the Intravaginal Therapies-Engineering Considerations”. Pharmaceutics 2021, 13, 1393; IF=7,227;
13. Piotr Ziemczonek, Monika Gosecka*, Mateusz Gosecki, Monika Marcinkowska, Anna Janaszewska, Barbara Klajnert-Maculewicz, „Star-Shaped Poly(furfuryl glycidyl ether)-Block-Poly(glyceryl glycerol ether) as an Efficient Agent for the Enhancement of Nifuratel Solubility and for the Formation of Injectable and Self-Healable Hydrogel Platforms for the Gynaecological Therapies”. International Journal of Molecular Sciences 2021, 22, DOI10.3390/ijms22168386; IF=5.924;
14. Mateusz Gosecki, Piotr Ziemczonek, Paulina Maczugowska,Anna Czaderna-Lekka, Marcin Kozanecki, Monika Gosecka* „The influence of 2-acrylamidephenylboronic acid on the phase behaviour of its copolymers with N-isopropylacrylamide in aqueous solution” Polymer Chemistry 2021, 12, 3264-3275; IF=5.582;
15. Monika Gosecka*, Mateusz Gosecki, Chemoresponsive polymer systems for selective molecular recognition of organic molecules in biological systems, Acta Biomaterialia, 116, 32-66, Elsevier, 2020, IF: 8.947,