Zainteresowania naukowe
• Implementacja, symulacje numeryczne i projektowanie nowych zaawansowanych technik spektroskopii NMR w ciele stałym
• Wdrażanie nowych metodologii NMR do analizy małych cząsteczek w cieczy
• Nowe strategie w syntezie i spektroskopii NMR porfirynoidów
• Chemia metaloorganiczna
• Nowoczesna synteza organiczna
Najważniejsze projekty badawcze
• 2018-2019 „Nowe metody rejestracji widm NMR w ciele stałym jąder o dużej anizotropii przesunięcia chemicznego” kierownik, grant na staż podoktorski w ramach programu „Mobilność Plus”
• 2012-2015 „Zastosowanie spektroskopii NMR w badaniach kompleksów supramolekularnych i koordynacyjnych” kierownik grantu NCN
Najważniejsze nagrody, wyróżnienia
• 2016 – Stypendium prezesa PAN za wybitne osiągnięcia
• 2016 – Stypendium START FNP
• 2015 – Stypendium START FNP
• 2015 – Stypendium firmy HRP „Nauka drogą do biznesu – program stypendialny dla doktorantów z woj. łódzkiego”
• 2010 – Stypendium Ministra Szkolnictwa Wyższego za Osiągnięcia w Nauce
• 2010 – Stypendium Marszałka Województwa Łódzkiego
• 2009 – Stypendium Ministra Szkolnictwa Wyższego za Osiągnięcia w Nauce
• 2009 – Student roku Wydziału Chemicznego PŁ w roku akademickim 2008/09
• 2008 – Stypendium Ministra Szkolnictwa Wyższego za Osiągnięcia w Nauce
• 2006 – Laureat (wyróżnienie) 52. Ogólnopolskiej Olimpiady Chemicznej
• 2005 – Brązowy medalista 37. Międzynarodowej Olimpiady Chemicznej, Tajpej, Tajwan
• 2004 – Laureat (wyróżnienie) 50. Ogólnopolskiej Olimpiady Chemicznej
• 2005 – Laureat (3 miejsce) 51. Ogólnopolskiej Olimpiady Chemicznej
Lista Publikacji
1. Paluch, P., Rankin, A.G.M., Trébosc, J., Lafon, O., Amoureux, J.-P. Analysis of HMQC experiments applied to a spin ½ nucleus subject to very large CSA (2019) Solid State Nuclear Magnetic Resonance, 100, pp. 11-25. DOI: 10.1016/j.ssnmr.2019.03.001
2. Jacek, P., Kubiak, K., Ryngajłło, M., Rytczak, P., Paluch, P., Bielecki, S. Modification of bacterial nanocellulose properties through mutation of motility related genes in Komagataeibacter hansenii ATCC 53582 (2019) New Biotechnology, 52, pp. 60-68.
3. Rankin, A.G.M., Trébosc, J., Paluch, P., Lafon, O., Amoureux, J.-P. Evaluation of excitation schemes for indirect detection of 14 N via solid-state HMQC NMR experiments (2019) Journal of Magnetic Resonance, 303, pp. 28-41. DOI: 10.1016/j.jmr.2019.04.004
4. Paluch, P., Pawlak, T., Lawniczak, K., Trébosc, J., Lafon, O., Amoureux, J.-P., Potrzebowski, M.J. Simple and Robust Study of Backbone Dynamics of Crystalline Proteins Employing 1H-15N Dipolar Coupling Dispersion (2018) Journal of Physical Chemistry B, 122 (34), pp. 8146-8156. DOI: 10.1021/acs.jpcb.8b04557
5. Dudek, M.K., Kostrzewa, M., Paluch, P., Potrzebowski, M.J. π-Philic Molecular Recognition in the Solid State as a Driving Force for Mechanochemical Formation of Apremilast Solvates and Cocrystals (2018) Crystal Growth and Design, 18 (7), pp. 3959-3970. DOI: 10.1021/acs.cgd.8b00301
6. Masnyk, M., Butkiewicz, A., Górecki, M., Luboradzki, R., Paluch, P., Potrzebowski, M.J., Frelek, J. In depth analysis of chiroptical properties of enones derived from abietic acid (2018) Journal of Organic Chemistry, 83 (7), pp. 3547-3561. DOI: 10.1021/acs.joc.7b02911
7. Śniechowska, J., Paluch, P., Pawlak, T., Bujacz, G.D., Danikiewicz, W., Potrzebowski, M.J.New synthetic pathway leading to oxospirochlorins (2018) RSC Advances, 8 (38), pp. 21354-21362. DOI: 10.1039/c8ra02445f
8. Głodek, M., Makal, A., Paluch, P., Kadziołka-Gaweł, M., Kobayashi, Y., Zakrzewski, J., Plazuk, D.(Ar-CO-CC)(PEt3)Au and (Ar-CC)(PEt3)Au complexes bearing pyrenyl and ferrocenyl groups: Synthesis, structure, and luminescence properties (2018) Dalton Transactions, 47 (19), pp. 6702-6712. DOI: 10.1039/c8dt01061g
9. Dudek, M.K., Wielgus, E., Paluch, P., Potrzebowski, M.J. Spontaneous Keto–Enol Tautomerization in the Crystal Lattice Visualized with the Help of Water Encapsulated in Hydrophilic Reservoirs (2017) ChemPhysChem, 18 (20), pp. 2850-2854. DOI: 10.1002/cphc.201700678
10. Paluch, P., Trébosc, J., Amoureux, J.-P., Potrzebowski, M.J. 1H-31P CPVC NMR method under Very Fast Magic Angle Spinning for analysis of dipolar interactions and dynamics processes in the crystalline phosphonium tetrafluoroborate salts (2017) Solid State Nuclear Magnetic Resonance, 87, pp. 96-103. DOI: 10.1016/j.ssnmr.2017.05.004
Liczba cytowań: 3, IF=2.365
11. Nagashima, H., Trébosc, J., Lafon, O., Pourpoint, F., Paluch, P., Potrzebowski, M.J., Amoureux, J.-P. Imaging the spatial distribution of radiofrequency field, sample and temperature in MAS NMR rotor (2017) Solid State Nuclear Magnetic Resonance, 87, pp. 137-142. DOI: 10.1016/j.ssnmr.2017.08.001
12. Paluch, P., Potrzebowska, N., Ruppert, A.M., Potrzebowski, M.J. Application of 1H and 27Al magic angle spinning solid state NMR at 60 kHz for studies of Au and Au-Ni catalysts supported on boehmite/alumina (2017) Solid State Nuclear Magnetic Resonance, 84, pp. 111-117. DOI: 10.1016/j.ssnmr.2017.01.005
13. Śniechowska, J., Paluch, P., Potrzebowski, M.J. Structure and dynamics processes in free-base chlorins controlled by chemical modifications of macroring and aryl groups in: Meso –positions (2017) RSC Advances, 7 (40), pp. 24795-24805. DOI: 10.1039/c7ra02217d
14. Wróblewska, A., Paluch, P., Wielgus, E., Bujacz, G., Dudek, M.K., Potrzebowski, M.J. Approach toward the understanding of coupling mechanism for EDC reagent in solvent-free mechanosynthesis (2017) Organic Letters, 19 (19), pp. 5360-5363. DOI: 10.1021/acs.orglett.7b02637
15. Dudek, M.K., Pawlak, T., Paluch, P., Jeziorna, A., Potrzebowski, M.J. A Multi-Technique Experimental and Computational Approach to Study the Dehydration Processes in the Crystals of Endomorphin Opioid Peptide Derivative (2016) Crystal Growth and Design, 16 (9), pp. 5312-5322. DOI: 10.1021/acs.cgd.6b00831
16. Nishiyama, Y., Malon, M., Potrzebowski, M.J., Paluch, P., Amoureux, J.P. Accurate NMR determination of C-H or N-H distances for unlabeled molecules (2016) Solid State Nuclear Magnetic Resonance, 73, pp. 15-21. DOI: 10.1016/j.ssnmr.2015.06.005
17. Śniechowska, J., Paluch, P., Bujacz, G., Górecki, M., Frelek, J., Gryko, D.T., Potrzebowski, M.J. Chiral crystals from porphyrinoids possessing a very low racemization barier (2016) CrystEngComm, 18 (20), pp. 3561-3565. DOI: 10.1039/c6ce00530f
18. Wielgus, E., Paluch, P., Frelek, J., Szczepek, W.J., Potrzebowski, M.J. Full Characterization of Linezolid and Its Synthetic Precursors by Solid-State Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry (2015) Journal of Pharmaceutical Sciences, 104 (11), pp. 3883-3892. DOI: 10.1002/jps.24606
19. Paluch, P., Pawlak, T., Jeziorna, A., Trébosc, J., Hou, G., Vega, A.J., Amoureux, J.-P., Dracinsky, M., Polenova, T., Potrzebowski, M.J. Analysis of local molecular motions of aromatic sidechains in proteins by 2D and 3D fast MAS NMR spectroscopy and quantum mechanical calculations (2015) Physical Chemistry Chemical Physics, 17 (43), pp. 28789-28801. DOI: 10.1039/c5cp04475h
20. Skorupska, E., Paluch, P., Jeziorna, A., Potrzebowski, M.J. NMR study of BA/FBA cocrystal confined within mesoporous silica nanoparticles employing thermal solid phase transformation (2015) Journal of Physical Chemistry C, 119 (16), pp. 8652-8661.
21. Sierant, M., Kazmierski, S., Rozanski, A., Paluch, P., Bienias, U., Miksa, B.J. Nanocapsules for 5-fluorouracil delivery decorated with a poly(2-ethylhexyl methacrylate-co-7-(4trifluoromethyl)coumarin acrylamide) cross-linked Wall (2015) New Journal of Chemistry, 39 (2), pp. 1506-1516. DOI: 10.1039/c4nj02053g
22. Paluch, P., Pawlak, T., Oszajca, M., Lasocha, W., Potrzebowski, M.J. Fine refinement of solid state structure of racemic form of phospho-tyrosine employing NMR Crystallography approach (2015) Solid State Nuclear Magnetic Resonance, 65, pp. 2-11. DOI: 10.1016/j.ssnmr.2014.08.002
23. Paluch, P., Trébosc, J., Nishiyama, Y., Potrzebowski, M.J., Malon, M., Amoureux, J.P. Theoretical study of CP-VC: A simple, robust and accurate MAS NMR method for analysis of dipolar C-H interactions under rotation speeds faster than ca. 60 kHz (2015) Journal of Magnetic Resonance, 252, pp. 67-77. DOI: 10.1016/j.jmr.2015.01.002
24. Bocian, W., Paluch, P., Nowak-Król, A., Gryko, D.T., Potrzebowski, M., Sniechowska, J., Sitkowski, J., Bednarek, E., Kozerski, L.The 1 H, 13 C, 15 N, and 19 F NMR chemical shifts assignments in 5,10,15-tris (pentafluorophenyl) tetra- 15 N corrole at 191 K (2014) Magnetic Resonance in Chemistry, 53 (2), pp. 167-171. DOI: 10.1002/mrc.4145
25. Huben, K., Jewgiński, M., Pabis, A., Paluch, P., Luy, B., Jankowski, S. The structure of cyclolinopeptide a in chloroform refined by RDC measurements (2014) Journal of Peptide Science, 20 (11), pp. 901-907. DOI: 10.1002/psc.2683
26. Skorupska, E., Jeziorna, A., Paluch, P., Potrzebowski, M.J. Ibuprofen in mesopores of mobil crystalline material 41 (MCM-41): A deeper understanding (2014) Molecular Pharmaceutics, 11 (5), pp. 1512-1519. DOI: 10.1021/mp400670f
27. Szymański, S., Paluch, P., Gryko, D.T., Nowak-Król, A., Bocian, W., Sitkowski, J., Koszarna, B., Śniechowska, J., Potrzebowski, M.J., Kozerski, L. Insights into the tautomerism in meso-substituted corroles: A variable-temperature 1 H, 13 C, 15 N, and 19 F NMR spectroscopy study(2014) Chemistry – A European Journal, 20 (6), pp. 1720-1730. DOI: 10.1002/chem.201303406
28. Jeziorna, A., Kazmierski, S., Paluch, P., Skorupska, E., Potrzebowski, M.J. Recent progress in the solid-state nmr studies of short peptides. techniques, structure and dynamics (2014) Annual Reports on NMR Spectroscopy, 83, pp. 67-143. DOI: 10.1016/B978-0-12-800183-7.00002-2
29. Pawlak, T., Paluch, P., Jeziorna, A., Bujacz, G.D., Potrzebowski, M.J. Slow and very fast MAS solid state NMR study of biopolymers (2014) Macromolecular Symposia, 339 (1), pp. 60-69. DOI: 10.1002/masy.201300139
30. Kobayashi, T., Mao, K., Paluch, P., Nowak-Krõl, A., Sniechowska, J., Nishiyama, Y., Gryko, D.T., Potrzebowski, M.J., Pruski, M. Study of intermolecular interactions in the corrole matrix by solid-state NMR under 100 kHz MAS and theoretical calculations (2013) Angewandte Chemie – International Edition, 52 (52), pp. 14108-14111. DOI: 10.1002/anie.201305475
31. Pawlak, T., Paluch, P., Trzeciak-Karlikowska, K., Jeziorna, A., Potrzebowski, M.J. Study of the thermal processes in molecular crystals of peptides by means of NMR crystallography (2013) CrystEngComm, 15 (43), pp. 8680-8692. DOI: 10.1039/c3ce40090e
32. Paluch, P., Kaźmierski, S., Jeziorna, A., Sniechowska, J., Dabrowa, K., Panek, J.J., Jezierska-Mazzarello, A., Jurczak, J., Potrzebowski, M.J. Influence of environmental humidity on organization and molecular dynamics of heteromacrocyclic assemblies (2013) Journal of Physical Chemistry B, 117 (46), pp. 14420-14431. DOI: 10.1021/jp406308a
33. Sierant, M., Paluch, P., Florczak, M., Rozanski, A., Miksa, B. Photosensitive nanocapsules for use in imaging from poly(styrene-co-divinylbenzene) cross-linked with coumarin derivatives (2013) Colloids and Surfaces B: Biointerfaces, 111, pp. 571-578. DOI: 10.1016/j.colsurfb.2013.07.002
34. Drabik, E., Jeziorna, A., Bienias, U., Trzeciak-Karlikowska, K., Pawlak, T., Paluch, P., Potrzebowski, M.J. Study of the mechanism of thermal chemical processes in the crystals of YAF tripeptides by means of mass spectrometry and solid state NMR (2013) Journal of Physical Chemistry B, 117 (43), pp. 13481-13489. DOI: 10.1021/jp407080q
35. Ghorbanloo, M., Jaworska, M., Paluch, P., Li, G.-D., Zhou, L.-J. Synthesis, characterization, and catalytic activity for thioanisole oxidation of homogeneous and heterogeneous binuclear manganese(II) complexes with amino acid-based ligands (2013) Transition Metal Chemistry, 38 (5), pp. 511-521. DOI: 10.1007/s11243-013-9718-4
36. Deredas, D., Albrecht, ., Maniukiewicz, W., Wojciechowski, J., Wolf, W.M., Paluch, P., Janecki, T., Rózalski, M., Krajewska, U., Janecka, A., Krawczyk, H. Three-component reaction of 3-(diethoxyphosphoryl)coumarin, enolizable ketones and primary amines: Simple, stereoselective synthesis of benzo[1,3]oxazocine skeletons (2013) RSC Advances, 3 (19), pp. 6821-6832
DOI: 10.1039/c3ra40184g
37. Midura, W.H., Sobczak, A., Paluch, P. Stereoselective cyclopropyl phosphonate formation using (S)-dimethylsulfonium-(p-tolylsulfinyl)methylide. Unusual phosphoryl group migration (2013) Tetrahedron Letters, 54 (3), pp. 223-226. DOI: 10.1016/j.tetlet.2012.11.002
38. Paluch, P., Pawlak, T., Amoureux, J.-P., Potrzebowski, M.J. Simple and accurate determination of X-H distances under ultra-fast MAS NMR (2013) Journal of Magnetic Resonance, 233, pp. 56-63. DOI: 10.1016/j.jmr.2013.05.005
39. Jeziorna, A., Pawlak, T., Trzeciak-Karlikowska, K., Paluch, P., Potrzebowski, M.J. Magic angle spinning NMR study of interaction of N-terminal sequence of dermorphin (Tyr-d-Ala-Phe-Gly) with phospholipids (2012) Biochimica et Biophysica Acta – Biomembranes, 1818 (11), pp. 2579-2587. DOI: 10.1016/j.bbamem.2012.06.013
40. Nowicka, K., Bujacz, A., Paluch, P., Sobczuk, A., Jeziorna, A., Ciesielski, W., Bujacz, G.D., Jurczak, J., Potrzebowski, M.J. Study of host-guest interactions in benzodiazacoronands by means of solid state NMR spectroscopy, X-ray diffraction and quantum mechanical computations(2011) Physical Chemistry Chemical Physics, 13 (14), pp. 6423-6433. DOI: 10.1039/c0cp02401e
41. Paluch, P., Potrzebowski, M.J. Combined solid state NMR and ONIOM studies of reversible crystalline phase reaction for nickel coordination compounds (2009) Solid State Nuclear Magnetic Resonance, 36 (2), pp. 103-109. DOI: 10.1016/j.ssnmr.2009.07.001
42. Pabis, A., Paluch, P., Szala, J., Paneth, P.A DFT study of the kinetic isotope effects on the competing SN2 and E2 reactions between hypochlorite anion and ethyl chloride (2009) Journal of Chemical Theory and Computation, 5 (1), pp. 33-36. DOI: 10.1021/ct800412h
